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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
My Experience On Jatenzo (Oral TRT) Log
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<blockquote data-quote="madman" data-source="post: 217784" data-attributes="member: 13851"><p><strong><em>post #41</em></strong></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/better-libido-sexual-function-with-different-esters.24730/page-3#post-216605[/URL]</p><p></p><p></p><p><strong><em>*In hypogonadal men with normal liver function, <u>400–600 mg testosterone must be administered daily if the patient is to be substituted by oral testosterone (Johnsen 1978; Johnsen et al. 1974), a dose exceeding the testosterone production of a normal man almost 100fold</u>. </em></strong><em><strong><u>Aside from being uneconomical, the possibility of adverse effects of such huge testosterone doses cannot be excluded, especially when given over long periods of time as required for substitution therapy</u>.</strong> <strong>However, in a <u>SMALL GROUP of patients treated for as long as seven years with oral testosterone, no serious side effects were observed (Johnson 1978)</u>. Nevertheless, oral administration of unmodified testosterone has not become a generally accepted method for therapeutic purposes.</strong></em></p><p></p><p></p><p><strong><em>*Historically, oral administration of physiological testosterone (Figure 1A) has been proven unsuccessful due to extensive first-pass metabolism through the liver despite having good gastrointestinal absorption.</em></strong><em> <strong><u>Ingestion of supra-physiological doses was required to overcome this and allow for measurable amounts in the serum</u> </strong></em></p><p></p><p></p><p></p><p></p><p>From a previous thread:</p><p></p><p><strong><em>post #355</em></strong></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/progesterone-dose-for-men.23247/page-18#post-217564[/URL]</p><p></p><p></p><p><strong>You stated:</strong></p><p></p><p><em>I’m currently not on estradiol. I’m not sure where my e2 sits but I presume it is on lower end. My most recent experiment involves 12mg of prop daily and</em><strong> <em>150mg of oral t base every 8ish hours </em></strong><em><strong>(3 times daily)</strong></em></p><p><em></em></p><p><em>Erectile quality skyrocketed for first time since being on trt. Still seeing whether or not this is honeymoon or not.</em></p></blockquote><p></p>
[QUOTE="madman, post: 217784, member: 13851"] [B][I]post #41[/I][/B] [URL unfurl="true"]https://www.excelmale.com/forum/threads/better-libido-sexual-function-with-different-esters.24730/page-3#post-216605[/URL] [B][I]*In hypogonadal men with normal liver function, [U]400–600 mg testosterone must be administered daily if the patient is to be substituted by oral testosterone (Johnsen 1978; Johnsen et al. 1974), a dose exceeding the testosterone production of a normal man almost 100fold[/U]. [/I][/B][I][B][U]Aside from being uneconomical, the possibility of adverse effects of such huge testosterone doses cannot be excluded, especially when given over long periods of time as required for substitution therapy[/U].[/B] [B]However, in a [U]SMALL GROUP of patients treated for as long as seven years with oral testosterone, no serious side effects were observed (Johnson 1978)[/U]. Nevertheless, oral administration of unmodified testosterone has not become a generally accepted method for therapeutic purposes.[/B][/I] [B][I]*Historically, oral administration of physiological testosterone (Figure 1A) has been proven unsuccessful due to extensive first-pass metabolism through the liver despite having good gastrointestinal absorption.[/I][/B][I] [B][U]Ingestion of supra-physiological doses was required to overcome this and allow for measurable amounts in the serum[/U] [/B][/I] From a previous thread: [B][I]post #355[/I][/B] [URL unfurl="true"]https://www.excelmale.com/forum/threads/progesterone-dose-for-men.23247/page-18#post-217564[/URL] [B]You stated:[/B] [I]I’m currently not on estradiol. I’m not sure where my e2 sits but I presume it is on lower end. My most recent experiment involves 12mg of prop daily and[/I][B] [I]150mg of oral t base every 8ish hours [/I][/B][I][B](3 times daily)[/B] Erectile quality skyrocketed for first time since being on trt. Still seeing whether or not this is honeymoon or not.[/I] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
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My Experience On Jatenzo (Oral TRT) Log
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