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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
My Experience On Jatenzo (Oral TRT) Log
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<blockquote data-quote="madman" data-source="post: 217777" data-attributes="member: 13851"><p>This is going to be huge!</p><p></p><p></p><p><strong>Significance Statement</strong></p><p></p><p><em><strong>There is no licensed oral testosterone because of challenges in formulation,</strong> and the oral formulations of the ester, testosterone undecanoate, require a fatty meal for absorption and generate supraphysiological dihydrotestosterone levels. <strong><em>We have overcome the design challenges and formulated <u>oral native testosterone</u> which can be taken<u> with or without food and provides physiological levels of testosterone and dihydrotestosterone in hypogonadal men</u>. </em>This formulation, <u>DITEST</u>, has the potential advantage of being oral for patients who don’t tolerate injections and less risk of adverse events that might theoretically be associated with elevated dihydrotestosterone levels</strong>. Future studies will need to define the dosing regimen for replacement in hypogonadal men.</em></p></blockquote><p></p>
[QUOTE="madman, post: 217777, member: 13851"] This is going to be huge! [B]Significance Statement[/B] [I][B]There is no licensed oral testosterone because of challenges in formulation,[/B] and the oral formulations of the ester, testosterone undecanoate, require a fatty meal for absorption and generate supraphysiological dihydrotestosterone levels. [B][I]We have overcome the design challenges and formulated [U]oral native testosterone[/U] which can be taken[U] with or without food and provides physiological levels of testosterone and dihydrotestosterone in hypogonadal men[/U]. [/I]This formulation, [U]DITEST[/U], has the potential advantage of being oral for patients who don’t tolerate injections and less risk of adverse events that might theoretically be associated with elevated dihydrotestosterone levels[/B]. Future studies will need to define the dosing regimen for replacement in hypogonadal men.[/I] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
My Experience On Jatenzo (Oral TRT) Log
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