Reply to thread

Hi Vince,

Up to 50% of the population have one of the, I believe, three types of MTHFR mutation.

It causes systemic inflammation by interfering with methyl group processing in the body.

It impacts homocysteine metabolism (it did for me). I just read Mayo Clinic notes on the mutation test... https://www.mayocliniclabs.com/testcatalog/Clinical+and+Interpretive/81648

...reserved for patients with acute disease... So we shouldn't know about it unless we are dying!  Sigh.

Supplement I used is 5-MTHF (5-methyltetrahydrofolate) 1000-4000 mcg. This is the one that is always highlighted for the MTHFR mutation.   Moved my homocysteine down from 13 to 9 and CRP from 5.5 to 0.82.

Is Methyl CPG better than straight 5-MTHF?  5-MTHF is included in a lot of B-complex supplements.

When I researched this I was leery of any product that has "folic acid" mentioned in ingredients.  I only take folate.