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General Health & Fitness
Nutrition and Supplements
MTHFR gene mutation
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<blockquote data-quote="hotdog" data-source="post: 168410" data-attributes="member: 12652"><p>Hi Vince, </p><p>Up to 50% of the population have one of the, I believe, three types of MTHFR mutation.</p><p>It causes systemic inflammation by interfering with methyl group processing in the body.</p><p>It impacts homocysteine metabolism (it did for me). I just read Mayo Clinic notes on the mutation test... <a href="https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/81648" target="_blank">https://www.mayocliniclabs.com/testcatalog/Clinical+and+Interpretive/81648</a></p><p>...reserved for patients with acute disease... So we shouldn't know about it unless we are dying! Sigh.</p><p></p><p>Supplement I used is 5-MTHF (5-methyltetrahydrofolate) 1000-4000 mcg. This is the one that is always highlighted for the MTHFR mutation. Moved my homocysteine down from 13 to 9 and CRP from 5.5 to 0.82.</p><p></p><p>Is Methyl CPG better than straight 5-MTHF? 5-MTHF is included in a lot of B-complex supplements.</p><p>When I researched this I was leery of any product that has "folic acid" mentioned in ingredients. I only take folate.</p></blockquote><p></p>
[QUOTE="hotdog, post: 168410, member: 12652"] Hi Vince, Up to 50% of the population have one of the, I believe, three types of MTHFR mutation. It causes systemic inflammation by interfering with methyl group processing in the body. It impacts homocysteine metabolism (it did for me). I just read Mayo Clinic notes on the mutation test... [URL='https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/81648']https://www.mayocliniclabs.com/testcatalog/Clinical+and+Interpretive/81648[/URL] ...reserved for patients with acute disease... So we shouldn't know about it unless we are dying! Sigh. Supplement I used is 5-MTHF (5-methyltetrahydrofolate) 1000-4000 mcg. This is the one that is always highlighted for the MTHFR mutation. Moved my homocysteine down from 13 to 9 and CRP from 5.5 to 0.82. Is Methyl CPG better than straight 5-MTHF? 5-MTHF is included in a lot of B-complex supplements. When I researched this I was leery of any product that has "folic acid" mentioned in ingredients. I only take folate. [/QUOTE]
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MTHFR gene mutation
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