more than 2 times a week IM injections

dallas101346

New Member
Does anyone do this. I am currently injecting 2x a week IM. My dose is 50mg T with 250IU HCG, same syringe, in the delt. I still feel like this is too big of a hormone shift for me each time, my head feels like its in a bubble a lot of times and I am not sure what is causing it. It isnt really fatigue or brain fog, just "head in a bubble" type feelings. Any idea whether I should try 3x a week injections to maybe keep things more stable. I have lowerish SHBG(15).

Could it be possible that my E2 is just a bit too high?
 
What is your E2 level? In fact, what are your blood levels across the board on this protocol?

Not 100% sure yet, as I have just come back on this protocol. Last time I was on this protocol my T was around 700 E2(ultraS) at 22. Maybe I just need more time to adapt to the influx of hormones.
 
Does anyone do this. I am currently injecting 2x a week IM. My dose is 50mg T with 250IU HCG, same syringe, in the delt. I still feel like this is too big of a hormone shift for me each time, my head feels like its in a bubble a lot of times and I am not sure what is causing it. It isnt really fatigue or brain fog, just "head in a bubble" type feelings. Any idea whether I should try 3x a week injections to maybe keep things more stable. I have lowerish SHBG(15).

Could it be possible that my E2 is just a bit too high?

At one point while I was injecting T, I was injecting 3 times a week. Shortly after starting 3 times a week (.15 M, .15 W, and .2 F) I started getting CONSISTENT morning wood and I was feeling somewhat better.

I hypothesized that if I could maintain my T levels more consistent, by minimizing the delta between highs and lows, my Estrogen levels would not fluctuate as much. I think I am very sensitive to Estrogen variations.

The best thing was that I needed no anastrozole.
 
That would probably work for me. I just worry about so many holes in the muscle. I have no issues injecting more, and trying to keep things stable. I too, think I must be pretty sensitive to E2 fluctuations. Even with 2 injections a week 50mg of T and 250IU will still cause a big E2 spike. But Id imagine 3 injections/ week will keep things more stable.

I have thought about subQ, but for some reason that converts at a higher rate to E2.
 
At a minimum, wait six weeks before making any changes to your protocol. If you have just resumed this particular one, be patient and allow your system to adjust to the levels it is experiencing. Do you have a good, open relationship with your doctor? If so, discuss this with him/her. But give it a chance - constant protocol changes create confusion across the board.
 
That would probably work for me. I just worry about so many holes in the muscle. I have no issues injecting more, and trying to keep things stable. I too, think I must be pretty sensitive to E2 fluctuations. Even with 2 injections a week 50mg of T and 250IU will still cause a big E2 spike. But Id imagine 3 injections/ week will keep things more stable.

I have thought about subQ, but for some reason that converts at a higher rate to E2.


But your estradiol reading was solidly in the 20s, wasn't it? You don't want to knock it much lower.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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