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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Microdosing Enanthate
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<blockquote data-quote="Cataceous" data-source="post: 239477" data-attributes="member: 38109"><p>Yes, this is going to be similar. With long-acting esters the minor dip in testosterone from missing a day probably isn't perceptible.</p><p></p><p></p><p>It applies to primary hypogonadism as well. Primary has the advantage of a normal body set point for its testosterone level—the testicles just can't produce enough to reach that level. For example, the hypothalamus and pituitary want total testosterone to be 650 ng/dL, but the testicles only produce enough to give you 200 ng/dL. With TRT you can dose to get close to the desired level without seeing HPTA shutdown—you're not exceeding what the hypothalamus and pituitary are calling for.</p><p></p><p>In secondary hypogonadism the body's set point is well below normal healthy levels; the hypothalamus or pituitary is hypersensitive and isn't requesting enough testosterone from the properly-functioning testicles. So, for example, they are satisfied when total testosterone reaches 200 ng/dL, even though this isn't a healthy level. When TRT puts you over this low set point the HPTA shuts down.</p><p></p><p></p><p>There's probably no harm in giving it a try. You might do well with it. My suspicion is that enclomiphene is more likely to give good results in those who naturally produce more estradiol. I'm in that category. It makes me wonder if guys with lower aromatization could actually do better with Clomid, where you're basically adding estrogen to your enclomiphene.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 239477, member: 38109"] Yes, this is going to be similar. With long-acting esters the minor dip in testosterone from missing a day probably isn't perceptible. It applies to primary hypogonadism as well. Primary has the advantage of a normal body set point for its testosterone level—the testicles just can't produce enough to reach that level. For example, the hypothalamus and pituitary want total testosterone to be 650 ng/dL, but the testicles only produce enough to give you 200 ng/dL. With TRT you can dose to get close to the desired level without seeing HPTA shutdown—you're not exceeding what the hypothalamus and pituitary are calling for. In secondary hypogonadism the body's set point is well below normal healthy levels; the hypothalamus or pituitary is hypersensitive and isn't requesting enough testosterone from the properly-functioning testicles. So, for example, they are satisfied when total testosterone reaches 200 ng/dL, even though this isn't a healthy level. When TRT puts you over this low set point the HPTA shuts down. There's probably no harm in giving it a try. You might do well with it. My suspicion is that enclomiphene is more likely to give good results in those who naturally produce more estradiol. I'm in that category. It makes me wonder if guys with lower aromatization could actually do better with Clomid, where you're basically adding estrogen to your enclomiphene. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Microdosing Enanthate
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