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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Michigan Phlebotomist and TRT Clinic?
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<blockquote data-quote="Cataceous" data-source="post: 238040" data-attributes="member: 38109"><p>You're injecting 196 mg of TC a week. That's approaching double the top end of normal testosterone production, and is about triple the production of average healthy young men. It's not remotely physiological. I assume HCT and HGB didn't rise with higher dosing because you'd already passed the saturation point with respect to effects on hepcidin.</p><p></p><p>What part of lower dosing didn't go well? When your body is accustomed to excess it can be uncomfortable to return to the physiological, but it's worth the effort.</p><p></p><p>If your absorption rate is typical then there's probably not going to be much benefit in increasing the dose frequency from EOD to daily, at least with a long-acting ester such as cypionate. On the other hand, a propionate blend should be injected daily, because it then creates a diurnal rhythm, somewhat mimicking natural variation in serum testosterone. The hypothesis is that some of the benefits of testosterone come from peak levels, whereas the side effects may be more correlated with trough or average levels.</p><p></p><p>You may not view it as realistic, but ideally you should spend a few months at 20 mg TC EOD to see what normal levels are really like. You can get there either via a slow taper or by going cold turkey. A sudden drop may be more traumatic, but a slow taper may also play with your mind, leaving you tempted to blame every problem on the slowly falling levels.</p><p></p><p>I've come across at least two guys with primary hypogonadism who successfully tuned their TRT doses to normalize their LH and FSH. There may be some independent benefits in having in-range LH.</p><p></p><p>For encouragement, here's my list of anecdotes from guys who found that lower is better:</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/anyone-combine-injections-and-cream-how-do-you-feel.22766/#post-195436[/URL]</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/for-those-who-are-struggling-on-trt.25592/[/URL]</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/numb-penis-anorgasmia-during-sex-low-cortisol-high-prolactin-on-trt.21461/post-230059[/URL]</p><p>[URL unfurl="true"]https://forums.t-nation.com/t/trt-most-probable-weekly-dose-range-for-treating-male-hypogonadism/270416/49[/URL]</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/anyone-combine-injections-and-cream-how-do-you-feel.22766/post-195136[/URL]</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/anyone-combine-injections-and-cream-how-do-you-feel.22766/post-196305[/URL]</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/hello-60yo-starting-trt.23181/post-198852[/URL]</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/have-you-ever-decreased-your-dose.6430/post-34989[/URL]</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/hello-60yo-starting-trt.23181/post-198831[/URL]</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/trt-patient-feeling-better-after-lowering-my-prescribed-dose.15352/[/URL]</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/dose-change-side-effects.23289/post-199912[/URL]</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/12mg-of-cypionate-causing-so-many-side-effects.22709/post-237584[/URL]</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/first-labs-after-starting-trt-wow.23483/post-212984[/URL]</p></blockquote><p></p>
[QUOTE="Cataceous, post: 238040, member: 38109"] You're injecting 196 mg of TC a week. That's approaching double the top end of normal testosterone production, and is about triple the production of average healthy young men. It's not remotely physiological. I assume HCT and HGB didn't rise with higher dosing because you'd already passed the saturation point with respect to effects on hepcidin. What part of lower dosing didn't go well? When your body is accustomed to excess it can be uncomfortable to return to the physiological, but it's worth the effort. If your absorption rate is typical then there's probably not going to be much benefit in increasing the dose frequency from EOD to daily, at least with a long-acting ester such as cypionate. On the other hand, a propionate blend should be injected daily, because it then creates a diurnal rhythm, somewhat mimicking natural variation in serum testosterone. The hypothesis is that some of the benefits of testosterone come from peak levels, whereas the side effects may be more correlated with trough or average levels. You may not view it as realistic, but ideally you should spend a few months at 20 mg TC EOD to see what normal levels are really like. You can get there either via a slow taper or by going cold turkey. A sudden drop may be more traumatic, but a slow taper may also play with your mind, leaving you tempted to blame every problem on the slowly falling levels. I've come across at least two guys with primary hypogonadism who successfully tuned their TRT doses to normalize their LH and FSH. There may be some independent benefits in having in-range LH. For encouragement, here's my list of anecdotes from guys who found that lower is better: [URL unfurl="true"]https://www.excelmale.com/forum/threads/anyone-combine-injections-and-cream-how-do-you-feel.22766/#post-195436[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/for-those-who-are-struggling-on-trt.25592/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/numb-penis-anorgasmia-during-sex-low-cortisol-high-prolactin-on-trt.21461/post-230059[/URL] [URL unfurl="true"]https://forums.t-nation.com/t/trt-most-probable-weekly-dose-range-for-treating-male-hypogonadism/270416/49[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/anyone-combine-injections-and-cream-how-do-you-feel.22766/post-195136[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/anyone-combine-injections-and-cream-how-do-you-feel.22766/post-196305[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/hello-60yo-starting-trt.23181/post-198852[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/have-you-ever-decreased-your-dose.6430/post-34989[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/hello-60yo-starting-trt.23181/post-198831[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/trt-patient-feeling-better-after-lowering-my-prescribed-dose.15352/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/dose-change-side-effects.23289/post-199912[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/12mg-of-cypionate-causing-so-many-side-effects.22709/post-237584[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/first-labs-after-starting-trt-wow.23483/post-212984[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
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Michigan Phlebotomist and TRT Clinic?
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