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Mental Health
Methylene Blue
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<blockquote data-quote="sammmy" data-source="post: 254270" data-attributes="member: 38594"><p>If it's too good to be true, probably it isn't ...</p><p></p><p>Anecdotal reports indicate MB acts like a stimulant but there are much safer herbal stimulants tested for thousands of years.</p><p></p><p>The whole hype revolves about MB acting as an anti-oxidant and somewhat comically improving the oxidation in mitochondria ... The whole hype of anti-oxidants somehow forgets that oxidation is the engine of life. They also never mention studies that show high doses of anti-oxidants lead to cancer in mice.</p><p></p><p>MB is also hyped up as an anti-aging topical at the microscopic concentration of 2.5 microMolar, however they found that at concentration 5 microMolar or higher it reduces epidermal cell viability i.e. is cytotoxic to skin cells. The cytotoxic concentration to mucosal cells is probably even lower so ingesting it probably kills cells in the intestines.</p><p></p><p>For reference, 1 microMolar of Methylene Blue is about 0.3mg dissolved in 1 Liter of water (1 Liter is about 1 quart = 4 cups).</p><p></p><p>Here is the study about the promoted "fountain of youth" that is cytotoxic at slightly higher concentration:</p><p></p><p>[URL unfurl="true"]https://www.nature.com/articles/s41598-017-02419-3#further-reading[/URL]</p></blockquote><p></p>
[QUOTE="sammmy, post: 254270, member: 38594"] If it's too good to be true, probably it isn't ... Anecdotal reports indicate MB acts like a stimulant but there are much safer herbal stimulants tested for thousands of years. The whole hype revolves about MB acting as an anti-oxidant and somewhat comically improving the oxidation in mitochondria ... The whole hype of anti-oxidants somehow forgets that oxidation is the engine of life. They also never mention studies that show high doses of anti-oxidants lead to cancer in mice. MB is also hyped up as an anti-aging topical at the microscopic concentration of 2.5 microMolar, however they found that at concentration 5 microMolar or higher it reduces epidermal cell viability i.e. is cytotoxic to skin cells. The cytotoxic concentration to mucosal cells is probably even lower so ingesting it probably kills cells in the intestines. For reference, 1 microMolar of Methylene Blue is about 0.3mg dissolved in 1 Liter of water (1 Liter is about 1 quart = 4 cups). Here is the study about the promoted "fountain of youth" that is cytotoxic at slightly higher concentration: [URL unfurl="true"]https://www.nature.com/articles/s41598-017-02419-3#further-reading[/URL] [/QUOTE]
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Mental Health
Methylene Blue
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