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General Health & Fitness
Health & Wellness
METFORMIN - no change in glucose readings
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<blockquote data-quote="Dialingitin" data-source="post: 229549" data-attributes="member: 44018"><p>Is your +/- 100 circulating glucose number tested in a fasted state (i.e., morning before eating)? If so, I'm not sure metformin supplementation would impact that reading since it (along with any diet-related glucose) would seem to be long gone from your system by the time you are pulling blood. Instead, your liver would be making glucose (gluconeogensis). </p><p></p><p>One of the functions of insulin is to effectively block gluconeogensis upon feeding, but that blocking function is compromised in those who have insulin resistance. With your glucose and A1c numbers, are you insulin resistant or have some spectrum of metabolic syndrome?</p><p></p><p>I'm super interested in this stuff because I've always hovered around 99/100 fasted glucose levels, regardless of how strict my keto diet and intermittent fasting schedule. Very frustrating and one of the reasons I am now giving GLP1 a try.</p></blockquote><p></p>
[QUOTE="Dialingitin, post: 229549, member: 44018"] Is your +/- 100 circulating glucose number tested in a fasted state (i.e., morning before eating)? If so, I'm not sure metformin supplementation would impact that reading since it (along with any diet-related glucose) would seem to be long gone from your system by the time you are pulling blood. Instead, your liver would be making glucose (gluconeogensis). One of the functions of insulin is to effectively block gluconeogensis upon feeding, but that blocking function is compromised in those who have insulin resistance. With your glucose and A1c numbers, are you insulin resistant or have some spectrum of metabolic syndrome? I'm super interested in this stuff because I've always hovered around 99/100 fasted glucose levels, regardless of how strict my keto diet and intermittent fasting schedule. Very frustrating and one of the reasons I am now giving GLP1 a try. [/QUOTE]
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General Health & Fitness
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METFORMIN - no change in glucose readings
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