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General Health & Fitness
Health & Wellness
Metformin Blocks Benefits of Aerobic Exercise on Insulin Sensitivity and VO2 max
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<blockquote data-quote="dnfuss" data-source="post: 157345" data-attributes="member: 15487"><p>Even though metformin's half life (~7hrs.) would suggest it should be fully gone in 36 hours or so, many diabetics have reported for years, and diabetologists have often observed this effect in their patients, that, just as metformin seems to take two to three weeks before the fullest effect is achieved, it seems to take two to three weeks off of it before most patients are truly back to "baseline." Perhaps there is some tissue saturation effect that is achieved and must be depleted when titrating off. Who knows? YMMV</p></blockquote><p></p>
[QUOTE="dnfuss, post: 157345, member: 15487"] Even though metformin's half life (~7hrs.) would suggest it should be fully gone in 36 hours or so, many diabetics have reported for years, and diabetologists have often observed this effect in their patients, that, just as metformin seems to take two to three weeks before the fullest effect is achieved, it seems to take two to three weeks off of it before most patients are truly back to "baseline." Perhaps there is some tissue saturation effect that is achieved and must be depleted when titrating off. Who knows? YMMV [/QUOTE]
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General Health & Fitness
Health & Wellness
Metformin Blocks Benefits of Aerobic Exercise on Insulin Sensitivity and VO2 max
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