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In this webinar for World Menopause Day, Dr. Louise and Dr. Rebecca discuss menopause and its connection to cardiovascular disease. They explain that menopause is the cessation of the ovaries’ hormone production, which can lead to various symptoms affecting multiple organs in the body. They emphasize the importance of hormone replacement therapy (HRT) in managing these symptoms and reducing the risk of heart disease. They also highlight the benefits of a healthy lifestyle and proper nutrition in maintaining heart health. The doctors refute the misconception that HRT increases the risk of heart disease and stress the need for individualized treatment based on symptoms and hormone balance.



Key Takeaway:


*Menopause is the year after the last natural period, characterized by a decline in hormonal production by the ovaries.


*Fluctuating estrogen levels during perimenopause can cause various symptoms, affecting multiple organs.


*The average age of menopause in the UK is 51, and early menopause refers to experiencing menopause before the age of 45.


*HRT is the most effective treatment for menopausal symptoms, improving overall well-being and reducing the risk of heart disease, osteoporosis, and type 2 diabetes.


*Hormones like estrogen, progesterone, and testosterone have a crucial role in maintaining heart health, reducing inflammation, improving blood flow, and reducing atheroma formation.


*Women who have an early menopause have an increased risk of heart disease, which can be lowered by taking HRT.


*Synthetic progestogens used in older types of HRT can have a small increased risk of cardiovascular disease.


*The Whi study contributed to the misconception that HRT increases the risk of heart disease, but newer types of HRT, including body-identical hormones, have shown a reduced risk.


*Women with heart conditions can usually take HRT safely, and the specific type and dose should be tailored to the individual.


*Hormone levels should be optimized, adjusting the dose and type as needed in order to effectively manage symptoms and improve heart health.


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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