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Unable to access the paper but it was suggested Hadley experienced an 8 hr erection along with other sides after inj melanotan II, that started the pursuit of a more specific peptide, PT 141. Hadley ME (October 2005). "Discovery that a melanocortin regulates sexual functions in male and female humans". Peptides. 26 (10): 1687–9. doi:10.1016/j.peptides.2005.01.023