Medicinal Mushrooms and Neurodegenerative Diseases

Will Brink

Member
Data continue to emerge suggesting various benefits,
including delaying of Neurodegenerative Diseases, depression, etc.

Article:

Mushrooms could prevent dementia and Alzheimer's disease, suggests study


New review:

Edible and Medicinal Mushrooms: Emerging Brain Food for the Mitigation of
Neurodegenerative Diseases

CW Phan et al. J Med Food 20 (1), 1-10. 1 2017.


Abstract

There is an exponential increase in dementia in old age at a global level
because of increasing life expectancy. The prevalence of neurodegenerative
diseases such as dementia and Alzheimer's disease (AD) will continue to
rise steadily, and is expected to reach 42 million cases worldwide in
2020.

Despite the advancement of medication, the management of these diseases
remains largely ineffective. Therefore, it is vital to explore novel
nature-based nutraceuticals to mitigate AD and other age-related
neurodegenerative disorders. Mushrooms and their extracts appear to hold
many health benefits, including immune-modulating effects.A number of
edible mushrooms have been shown to contain rare and exotic compounds that
exhibit positive effects on brain cells both in vitro and in vivo.

In this review, we summarize the scientific information on edible and
culinary mushrooms with regard to their antidementia/AD active compounds
and/or pharmacological test results. The bioactive components in these
mushrooms and the underlying mechanism of their activities are discussed.
In short, these mushrooms may be regarded as functional foods for the
mitigation of neurodegenerative diseases.



https://www.ncbi.nlm.nih.gov/labs/articles/28098514/
 

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Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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