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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Managing Hair Loss: Comprehensive Review
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<blockquote data-quote="Nelson Vergel" data-source="post: 269395" data-attributes="member: 3"><p>Tofacitinib is a Janus kinase (JAK) inhibitor that has been shown to improve hair loss in patients with alopecia areata (AA) [2][3][4][5][6]. AA is an autoimmune disease that causes hair loss on the scalp and other parts of the body. Tofacitinib is available in oral and topical formulations and has been used to treat patients with more severe and longstanding disease[3]. </p><p></p><p>While tofacitinib has been shown to be effective in treating AA, it is important to note that it may have side effects. For example, one patient developed hyperlipidemia and weight gain while on 11 mg extended release twice daily[3]. Additionally, further clinical trials are required to establish whether the use of tofacitinib citrate in combating AA, as well as potentially other forms of hair loss, is safe[5]. </p><p></p><p>In summary, tofacitinib is a JAK inhibitor that has been shown to improve hair loss in patients with AA. However, it may have side effects, and further clinical trials are needed to establish its safety.</p><p></p><p>Sources</p><p>[1] LONG-TERM TREATMENT WITH TOFACITINIB IN SEVERE ALOPECIA AREATA: AN UPDATE - PMC - NCBI <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624004/" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624004/</a></p><p>[2] Treatment of Alopecia Areata With Tofacitinib - PMC - NCBI <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817614/" target="_blank">Treatment of Alopecia Areata With Tofacitinib</a></p><p>[3] Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib - JDDonline <a href="https://jddonline.com/articles/successful-treatment-of-severe-alopecia-areata-with-oral-or-topical-tofacitinib-S1545961618P0800X" target="_blank">Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib - JDDonline - Journal of Drugs in Dermatology</a></p><p>[4] Treatment of Alopecia Areata With Tofacitinib | Targeted and Immune Cancer Therapy <a href="https://jamanetwork.com/journals/jamadermatology/fullarticle/2612720" target="_blank">https://jamanetwork.com/journals/jamadermatology/fullarticle/2612720</a></p><p>[5] Treating Alopecia Universalis with Xeljanz May Have Serious Side Effects <a href="https://www.belgraviacentre.com/blog/treating-alopecia-universalis-with-arthritis-drug-xeljanz-may-have-serious-side-effects" target="_blank">Treating Alopecia Universalis with Xeljanz May Have Serious Side Effects</a></p><p>[6] Changing the Lives of Patients With Alopecia and Vitiligo < Yale School of Medicine <a href="https://medicine.yale.edu/news-article/changing-the-lives-of-patients-with-alopecia-and-vitiligo/" target="_blank">Changing the Lives of Patients With Alopecia and Vitiligo</a></p><p></p><p>By Perplexity at <a href="https://www.perplexity.ai/search/46ae4804-2bb2-4b30-a904-93d593148c70" target="_blank">https://www.perplexity.ai/search/46ae4804-2bb2-4b30-a904-93d593148c70</a></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 269395, member: 3"] Tofacitinib is a Janus kinase (JAK) inhibitor that has been shown to improve hair loss in patients with alopecia areata (AA) [2][3][4][5][6]. AA is an autoimmune disease that causes hair loss on the scalp and other parts of the body. Tofacitinib is available in oral and topical formulations and has been used to treat patients with more severe and longstanding disease[3]. While tofacitinib has been shown to be effective in treating AA, it is important to note that it may have side effects. For example, one patient developed hyperlipidemia and weight gain while on 11 mg extended release twice daily[3]. Additionally, further clinical trials are required to establish whether the use of tofacitinib citrate in combating AA, as well as potentially other forms of hair loss, is safe[5]. In summary, tofacitinib is a JAK inhibitor that has been shown to improve hair loss in patients with AA. However, it may have side effects, and further clinical trials are needed to establish its safety. Sources [1] LONG-TERM TREATMENT WITH TOFACITINIB IN SEVERE ALOPECIA AREATA: AN UPDATE - PMC - NCBI [URL]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624004/[/URL] [2] Treatment of Alopecia Areata With Tofacitinib - PMC - NCBI [URL="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817614/"]Treatment of Alopecia Areata With Tofacitinib[/URL] [3] Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib - JDDonline [URL="https://jddonline.com/articles/successful-treatment-of-severe-alopecia-areata-with-oral-or-topical-tofacitinib-S1545961618P0800X"]Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib - JDDonline - Journal of Drugs in Dermatology[/URL] [4] Treatment of Alopecia Areata With Tofacitinib | Targeted and Immune Cancer Therapy [URL]https://jamanetwork.com/journals/jamadermatology/fullarticle/2612720[/URL] [5] Treating Alopecia Universalis with Xeljanz May Have Serious Side Effects [URL="https://www.belgraviacentre.com/blog/treating-alopecia-universalis-with-arthritis-drug-xeljanz-may-have-serious-side-effects"]Treating Alopecia Universalis with Xeljanz May Have Serious Side Effects[/URL] [6] Changing the Lives of Patients With Alopecia and Vitiligo < Yale School of Medicine [URL="https://medicine.yale.edu/news-article/changing-the-lives-of-patients-with-alopecia-and-vitiligo/"]Changing the Lives of Patients With Alopecia and Vitiligo[/URL] By Perplexity at [URL]https://www.perplexity.ai/search/46ae4804-2bb2-4b30-a904-93d593148c70[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
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Managing Hair Loss: Comprehensive Review
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