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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Male infertility and intratesticular T - insight into novel serum biomarkers
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<blockquote data-quote="madman" data-source="post: 217413" data-attributes="member: 13851"><p><strong>Fig. 2 <u>The biosynthesis of 17-OHP and testosterone</u>. The synthesis pathway of 17-OHP begins with cholesterol and doesn’t reach the ITT stage until androstenedione is processed. Note the difference between intratesticular testosterone and serum testosterone as the concentrations differ greatly in passing the blood-testis barrier. Then once endocrine secretion is achieved by the Leydig cell T is transformed into estradiol and DHT. A great portion of which is done via aromatase found within adipose tissue, potentially demonstrating the link between BMI and 17-OHP indirectly via downstream feedback.</strong></p><p><strong>[ATTACH=full]19723[/ATTACH]</strong></p></blockquote><p></p>
[QUOTE="madman, post: 217413, member: 13851"] [B]Fig. 2 [U]The biosynthesis of 17-OHP and testosterone[/U]. The synthesis pathway of 17-OHP begins with cholesterol and doesn’t reach the ITT stage until androstenedione is processed. Note the difference between intratesticular testosterone and serum testosterone as the concentrations differ greatly in passing the blood-testis barrier. Then once endocrine secretion is achieved by the Leydig cell T is transformed into estradiol and DHT. A great portion of which is done via aromatase found within adipose tissue, potentially demonstrating the link between BMI and 17-OHP indirectly via downstream feedback. [ATTACH type="full"]19723[/ATTACH][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Male infertility and intratesticular T - insight into novel serum biomarkers
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