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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Male Hypogonadism
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<blockquote data-quote="tareload" data-source="post: 225275"><p><em></em></p><p><em>About as good as you are going to get best case with routine and methodical calibration.</em></p><p></p><p>[URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620848/#!po=48.3051[/URL]</p><p></p><p></p><h3>Methods</h3><p>This study compares the results from four independently developed and validated LC-MS/MS assays for total testosterone. The calibration for each assay was verified using National Institute of Standards and Technology Standard Reference Material 971.</p><p></p><h3>Conclusions</h3><p>Excellent agreement between four independently developed LC-MS/MS assays demonstrates that harmonization using standard reference material is attainable. However, as we found in this study, to ensure accurate calibration it is critical to validate the concentrations of new lots of calibrators</p></blockquote><p></p>
[QUOTE="tareload, post: 225275"] [I] About as good as you are going to get best case with routine and methodical calibration.[/I] [URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620848/#!po=48.3051[/URL] [HEADING=2]Methods[/HEADING] This study compares the results from four independently developed and validated LC-MS/MS assays for total testosterone. The calibration for each assay was verified using National Institute of Standards and Technology Standard Reference Material 971. [HEADING=2]Conclusions[/HEADING] Excellent agreement between four independently developed LC-MS/MS assays demonstrates that harmonization using standard reference material is attainable. However, as we found in this study, to ensure accurate calibration it is critical to validate the concentrations of new lots of calibrators [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Male Hypogonadism
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