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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Maintaining LH & FSH on TRT
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<blockquote data-quote="Cataceous" data-source="post: 215012" data-attributes="member: 38109"><p>I wasn't aware that Primebody was into this. Any links to sample protocols? What I have seen is Royal Medical Center giving infrequent very large doses of gonadorelin. <a href="https://www.royalmedicalcenters.com/gonadorelin/" target="_blank">Their results</a> suggest that this does lead to normal FSH and LH in those on TRT, at least for a limited period after each injection. What's less clear is whether the subjective results are at all comparable to those seen when using hCG, or when using somewhat <a href="https://www.excelmale.com/forum/threads/pituitary-restart-while-on-trt-promising-initial-results-with-gnrh-plus-enclomiphene.20864/" target="_blank">more realistic dosing of gonadorelin</a>. Normally men have more like 10-20 pulses of LH each day. It seems questionable that eliciting two pulses a week with very large amounts of gonadorelin is remotely similar.</p><p></p><p>The reason why you haven't been able to maintain LH and FSH on TRT is because androgens independently provide negative feedback to the hypothalamus, suppressing GnRH production. GnRH is the signal to the pituitary to make LH. Estrogens create negative feedback at both the hypothalamus and the pituitary, but this can be blocked with a SERM such as Clomid.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 215012, member: 38109"] I wasn't aware that Primebody was into this. Any links to sample protocols? What I have seen is Royal Medical Center giving infrequent very large doses of gonadorelin. [URL='https://www.royalmedicalcenters.com/gonadorelin/']Their results[/URL] suggest that this does lead to normal FSH and LH in those on TRT, at least for a limited period after each injection. What's less clear is whether the subjective results are at all comparable to those seen when using hCG, or when using somewhat [URL='https://www.excelmale.com/forum/threads/pituitary-restart-while-on-trt-promising-initial-results-with-gnrh-plus-enclomiphene.20864/']more realistic dosing of gonadorelin[/URL]. Normally men have more like 10-20 pulses of LH each day. It seems questionable that eliciting two pulses a week with very large amounts of gonadorelin is remotely similar. The reason why you haven't been able to maintain LH and FSH on TRT is because androgens independently provide negative feedback to the hypothalamus, suppressing GnRH production. GnRH is the signal to the pituitary to make LH. Estrogens create negative feedback at both the hypothalamus and the pituitary, but this can be blocked with a SERM such as Clomid. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Maintaining LH & FSH on TRT
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