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Decreases lipoprotein(a)—Among the most serious of heart disease risk factors, no other treatment approaches the power of niacin to reduce this genetically-determined pattern.


Extended- or intermediate-release niacin are time-release preparations, but not as slow as slow-release. This has made them safer than the slow-release preparations that can cause liver side-effects. It also provokes less hot flush than immediate-release. Over-the-counter Slo-Niacin®, is one such preparation and has been proven to be safe (Brown 2001). Niaspan® (Kos Pharmaceuticals) is a prescription extended-release preparation.


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