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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
low testosterone vs low thyroid
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<blockquote data-quote="madman" data-source="post: 106078" data-attributes="member: 13851"><p>Scroll to page 13-14 and look over Table 4: Assays For The Diagnosis Of Teststerone Deficiency and look under assay for Free TESTOSTERONE and you will see the difference in co-efficient of variation, adavantages/disadvantages between equilibrium dialysis, calculated method and direct (ultracentrifugation, analog)</p><p></p><p>As you will see the EQUILIBRIUM DIALYSIS- co-efficent of variation for intra assay is 10% and inter assay is 6.8%</p><p></p><p>-advantages of equilibrium dialysis - considered gold standard and has excellent sensitivity/specifity</p><p>-disadvantages- labor intensive, low throughput</p><p></p><p></p><p></p><p>As you will see CALCULATED METHOD- co-efficient of variation is 18-30%</p><p></p><p>-advantages of calculated method - rapid, simple, has correlated in some series (BUT NOT ALL) well with equilibrium dialysis</p><p>-disadvantages- relies on TT and SHBG assay accuracy, accuracy relies on equilibrium dissociation constants for binding of SHBG and albumin to testosterone, higher inter-assay variability</p></blockquote><p></p>
[QUOTE="madman, post: 106078, member: 13851"] Scroll to page 13-14 and look over Table 4: Assays For The Diagnosis Of Teststerone Deficiency and look under assay for Free TESTOSTERONE and you will see the difference in co-efficient of variation, adavantages/disadvantages between equilibrium dialysis, calculated method and direct (ultracentrifugation, analog) As you will see the EQUILIBRIUM DIALYSIS- co-efficent of variation for intra assay is 10% and inter assay is 6.8% -advantages of equilibrium dialysis - considered gold standard and has excellent sensitivity/specifity -disadvantages- labor intensive, low throughput As you will see CALCULATED METHOD- co-efficient of variation is 18-30% -advantages of calculated method - rapid, simple, has correlated in some series (BUT NOT ALL) well with equilibrium dialysis -disadvantages- relies on TT and SHBG assay accuracy, accuracy relies on equilibrium dissociation constants for binding of SHBG and albumin to testosterone, higher inter-assay variability [/QUOTE]
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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
low testosterone vs low thyroid
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