Low Testosterone Levels in Men: What’s Really “Low” and When to Consider HRT

madman · Sunday at 5:27 PM

DEBATE: WHAT IS A LOW TESTOSTERONE?

Professor Geoffrey Hackett

Professor Shalender Bhasin

Synthesis

madman · Sunday at 5:31 PM

Benefits of Testosterone Therapy in men with Low Testosterone

madman · Sunday at 5:37 PM

14 year follow up study from the EMAS data

UK Biobank study

Three main studies: T Trial, TRAVERSE and T4DM

The T Trial

madman · Sunday at 5:40 PM

Long Term Cardiovascular Safety of Testosterone Therapy: A review of the TRAVERSE Study

madman · Sunday at 5:47 PM

The T4DM study

T4DM Secondary outcomes at 2 years

The BLAST study

When we looked at mortality from the BLAST study

madman · Sunday at 5:49 PM

Recent FDA Update

madman · Sunday at 5:52 PM

Society for Endocrinology guidelines

BSSM Guidelines

Thread 'British Society for Sexual Medicine Guidelines on Male Adult TD'

Mar 9, 2023

The British Society for Sexual Medicine Guidelines on Male Adult Testosterone Deficiency, With Statements for Practice (2023)
Geoffrey Hackett, Michael Kirby, Rowland W. Rees, T. Hugh Jones, Asif Muneer, Mark Livingston, Nick Ossei-Gerning, Janine David, Jeff Foster, Philip A. Kalra, Sudarshan Ramachandran

Testosterone deficiency (TD) is an increasingly common problem with significant health implications, but its diagnosis and management can be challenging. A multi-disciplinary panel from BSSM reviewed the available literature on TD and provide evidence-based statements for...

madman · Sunday at 5:57 PM

STARRR3!

What is a "Low" Testosterone Level?

The Pivotol Tenets of Endocrinology

Synthesis

Thread 'Dr. Shalender Bhasin: Optimizing the Diagnosis and Treatment of Hypogonadism 2025'

Oct 7, 2025

Nelson's house u heard it here first!

Dr. Shalender Bhasin!

* over the past 4 decades he has become a global leader in the biology of androgens, sarcopenia and aging related functional decline, his research has shaped clinical guidelines, its informed public health policy particularly around testosterone therapy, anabolic interventions and then the development of function promoting therapies

Pay attention to 25:40-34:36 of the presentation where he explains the importance of measuring free testosterone using a standardized Equilibrium Dialysis method!

Explains the...

madman · 2026-02-25T16:33:21-0600

Approaches to Defining Endocrine Disorders

madman · 2026-02-25T16:34:31-0600

Generating the "Reference Sample"

madman · 2026-02-25T16:46:37-0600

The BWH-CDC Collaboration to Generate harmonized Reference Ranges for Testosterone under Auspices of End Society (2009-2017)

Distribution of CDC-standardized circulating total testosterone measurements among healthy men of age 19-39 years, N =1656

* these are the statically based references ranges derived from this rigorously collected sample using harmonized LC/MS-MS assay benchmarked to a higher order calibrator. So these values are robust. They are commutable to a definable reference preparation and they are immutable.