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James

Nydheart has not told us what his total T level is.

If I had no low libido or ED, I would not start TRT unless two fasting morning samples taken a month apart showed TT < 250 ng/dL. I know that sounds super conservative coming from me.

Yes, lower TT has been associated with higher risk of diabetes, heart disease, and metabolic syndrome. But the studies that looked into these associations did not measure free T and DHT.

Good libido and strong erections are things to cherish and protect. Introducing TRT and its HTPA shutdown may jeopardize these two factors.

Some men's bodies can do better than others with lower TT. Most of these men have free T over 3 percent of total and great levels of other androgens/metabolites like DHT and DHEA. Unfortunately, most TRT and hypogonadism studies have only measured total testosterone and not free T or DHT, two of the strongest factors in my opinion on sex drive and erection quality in men.

<blockquote data-quote="Nelson Vergel" data-source="post: 16071" data-attributes="member: 3">JamesNydheart has not told us what his total T level is.If I had no low libido or ED, I would not start TRT unless two fasting morning samples taken a month apart showed TT &lt; 250 ng/dL.&nbsp; I know that sounds super conservative coming from me.Yes, lower TT has been associated with higher risk of diabetes, heart disease, and metabolic syndrome.&nbsp; But the studies that looked into these associations did not measure free T and DHT.Good libido and strong erections are things to cherish and protect. Introducing TRT and its HTPA shutdown may jeopardize these two factors.Some men&#039;s bodies can do better than others with lower TT.&nbsp; Most of these men have free T over 3 percent of total and great levels of other androgens/metabolites like DHT and DHEA. Unfortunately, most TRT and hypogonadism studies have only measured total testosterone and not free T or DHT, two of the strongest factors in my opinion on sex drive and erection quality in men.</blockquote>

[QUOTE="Nelson Vergel, post: 16071, member: 3"] James Nydheart has not told us what his total T level is. If I had no low libido or ED, I would not start TRT unless two fasting morning samples taken a month apart showed TT < 250 ng/dL. I know that sounds super conservative coming from me. Yes, lower TT has been associated with higher risk of diabetes, heart disease, and metabolic syndrome. But the studies that looked into these associations did not measure free T and DHT. Good libido and strong erections are things to cherish and protect. Introducing TRT and its HTPA shutdown may jeopardize these two factors. Some men's bodies can do better than others with lower TT. Most of these men have free T over 3 percent of total and great levels of other androgens/metabolites like DHT and DHEA. Unfortunately, most TRT and hypogonadism studies have only measured total testosterone and not free T or DHT, two of the strongest factors in my opinion on sex drive and erection quality in men. [/QUOTE]

Verification

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038