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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Low T levels increase damage in artheriosclerosis
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<blockquote data-quote="Jinzang" data-source="post: 191679" data-attributes="member: 12925"><p>It's an animal study, but probably relevant to men. It's best not to eat an unhealthy diet, but it's good to know that testosterone protects against heart artery damage. The <a href="https://link.springer.com/article/10.1007/s11010-020-03987-1" target="_blank">abstract</a> says:</p><p></p><p>"To gain insights into the role of testosterone in the development of atherosclerosis and its related metabolic pathways, we investigated urine metabolic profiles in miniature pigs fed a high-fat and high-cholesterol (HFC) diet among intact male pigs (IM), castrated male pigs (CM) and castrated male pigs with testosterone replacement (CMT). Our results showed that testosterone deficiency significantly increased atherosclerotic lesion areas, intima-media thickness, as well as serum lipid levels in the CM pigs. Our study demonstrated that testosterone deficiency accelerated early AS formation in HFC diet-fed pigs, which involved several metabolites predominantly related to lipid metabolism, inflammation, oxidative stress and endothelial disorders. Our results reveal potential pathways in the pathogenesis of atherosclerosis caused by testosterone deficiency and HFC diet."</p></blockquote><p></p>
[QUOTE="Jinzang, post: 191679, member: 12925"] It's an animal study, but probably relevant to men. It's best not to eat an unhealthy diet, but it's good to know that testosterone protects against heart artery damage. The [URL='https://link.springer.com/article/10.1007/s11010-020-03987-1']abstract[/URL] says: "To gain insights into the role of testosterone in the development of atherosclerosis and its related metabolic pathways, we investigated urine metabolic profiles in miniature pigs fed a high-fat and high-cholesterol (HFC) diet among intact male pigs (IM), castrated male pigs (CM) and castrated male pigs with testosterone replacement (CMT). Our results showed that testosterone deficiency significantly increased atherosclerotic lesion areas, intima-media thickness, as well as serum lipid levels in the CM pigs. Our study demonstrated that testosterone deficiency accelerated early AS formation in HFC diet-fed pigs, which involved several metabolites predominantly related to lipid metabolism, inflammation, oxidative stress and endothelial disorders. Our results reveal potential pathways in the pathogenesis of atherosclerosis caused by testosterone deficiency and HFC diet." [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Low T levels increase damage in artheriosclerosis
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