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Low SHBG
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<blockquote data-quote="MarkM" data-source="post: 116290"><p>That's a pretty stiff does of testosterone each week along with a very high dose of arimidex. Arimidex at larger doses has many unwanted side effects over time. It's likely you would not need the arimidex if you lowered you testosterone consumption. You have very low SHBG so you are probably peeing out a lot of your testosterone.</p><p></p><p>Total Testosterone isn't what's important, it the Free Testosterone It's probably on the high side, which you want to a degree but you probably have high Free Estradiol too which you don't want. Most people with low SHBG like you have need smaller doses and more frequent injections for them to have success with TRT. </p><p></p><p>Have you considered daily injections? Smaller doses on a daily bases will likely raise you test and you could probably get rid of taking the arimidex because you are not going to have it spiking from the larger test injections. Is the estradiol test the Estradiol Sensitive, LC/MS/MS assay? </p><p></p><p>Do you have labs that you can post so we can see everything in it's entirety so we can see ranges and offer up more credible advice.</p></blockquote><p></p>
[QUOTE="MarkM, post: 116290"] That's a pretty stiff does of testosterone each week along with a very high dose of arimidex. Arimidex at larger doses has many unwanted side effects over time. It's likely you would not need the arimidex if you lowered you testosterone consumption. You have very low SHBG so you are probably peeing out a lot of your testosterone. Total Testosterone isn't what's important, it the Free Testosterone It's probably on the high side, which you want to a degree but you probably have high Free Estradiol too which you don't want. Most people with low SHBG like you have need smaller doses and more frequent injections for them to have success with TRT. Have you considered daily injections? Smaller doses on a daily bases will likely raise you test and you could probably get rid of taking the arimidex because you are not going to have it spiking from the larger test injections. Is the estradiol test the Estradiol Sensitive, LC/MS/MS assay? Do you have labs that you can post so we can see everything in it's entirety so we can see ranges and offer up more credible advice. [/QUOTE]
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