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Has anyone ever clarified the difference between naturally low SHBG and TRT induced low low SHBG????  do we consider and treat natural/TRT imposed low SHBG the same?


My SHBG prior to TRT was averaging in the mid-high 30's, however, since starting TRT my SHBG has been single digit to high teens... I do notice the higher the TRT dosage the lower my SHBG goes.


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