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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Low SHBG ! Good or bad?
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<blockquote data-quote="TRicker" data-source="post: 218478" data-attributes="member: 42831"><p>[USER=1210]@ERO[/USER] Have you found anything that works for you yet?</p><p></p><p>I found it interesting what Dr Mariano states, from [USER=2810]@Okian[/USER] post above:</p><p></p><p>He states that high shbg guys need lower doses of testosterone, because SHBG prolongs testosterone's action. Would this imply low SHBG guys actually need higher doses (the opposite of current advice)?</p><p>He also states that he considers total testosterone more important than free t, because total t indicates more signaling capacity (also the opposite of current advice). He stated that free testosterone often times does not determine libido.</p><p></p><p>I also have low shbg, and definitely felt better when I began TRT with the typical clinic protocol of 200mg test cyp 1x/week, hcg, anastrozole. I didn't feel awesome, but better compared to lower dosages, split 2x/week dosages, 3x/week subq (subq for me really brought my t numbers down quite a bit). </p><p>My T Clinic has thousands of patients, and I'm one of their few problem cases. They probably are a "typical T mill", but I guess their approach is working for a lot of guys.</p><p></p><p>As a side note: I was on enclomiphene-only for 5 months for fertility purposes, and although in definitely increased my sperm count, my total testosterone never got above 300. Interestingly, after 8 weeks of enclo my shbg was around 18, after 12 weeks my shbg was around 18, BUT after 16 weeks on enclo my shbg jumped up to 30. Maybe TRT plus clom/enclo could raise shbg?</p><p></p><p>[USER=13328]@Jason Sypolt[/USER] have you tried adding clomiphene/enclomiphene to your protocol?</p><p>If you don't mind, can you say what protocol your on now and what's working for you with low shbg?</p><p></p><p>Thank you in advance for any suggestions!</p></blockquote><p></p>
[QUOTE="TRicker, post: 218478, member: 42831"] [USER=1210]@ERO[/USER] Have you found anything that works for you yet? I found it interesting what Dr Mariano states, from [USER=2810]@Okian[/USER] post above: He states that high shbg guys need lower doses of testosterone, because SHBG prolongs testosterone's action. Would this imply low SHBG guys actually need higher doses (the opposite of current advice)? He also states that he considers total testosterone more important than free t, because total t indicates more signaling capacity (also the opposite of current advice). He stated that free testosterone often times does not determine libido. I also have low shbg, and definitely felt better when I began TRT with the typical clinic protocol of 200mg test cyp 1x/week, hcg, anastrozole. I didn't feel awesome, but better compared to lower dosages, split 2x/week dosages, 3x/week subq (subq for me really brought my t numbers down quite a bit). My T Clinic has thousands of patients, and I'm one of their few problem cases. They probably are a "typical T mill", but I guess their approach is working for a lot of guys. As a side note: I was on enclomiphene-only for 5 months for fertility purposes, and although in definitely increased my sperm count, my total testosterone never got above 300. Interestingly, after 8 weeks of enclo my shbg was around 18, after 12 weeks my shbg was around 18, BUT after 16 weeks on enclo my shbg jumped up to 30. Maybe TRT plus clom/enclo could raise shbg? [USER=13328]@Jason Sypolt[/USER] have you tried adding clomiphene/enclomiphene to your protocol? If you don't mind, can you say what protocol your on now and what's working for you with low shbg? Thank you in advance for any suggestions! [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Low SHBG ! Good or bad?
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