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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Low progesterone? Frustrated. Thinking of pulling the plug on TRT for good.
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<blockquote data-quote="Cataceous" data-source="post: 181512" data-attributes="member: 38109"><p>This is a garbled interpretation. Gonadorelin is bio-identical to GnRH. Natural men function by producing GnRH pulses for most of their lives. That, in effect, is extremely prolonged use. The kind of "prolonged use" you refer to as causing suppression is actually a continuous infusion of GnRH, rather then the intermittent pulses required by our bodies. This is just something described in research; it's not a treatment. It becomes a treatment intended to cause HPTA suppression when longer-lived GnRH analogs such as triptorelin are used. On the flip side, pulsed doses of gonadorelin are an approved treatment for male hypogonadism; they are proven to normalize the gonadotropins and testosterone. The need for an infusion pump is what limits its appeal. I <a href="https://www.excelmale.com/forum/threads/pituitary-restart-while-on-trt-promising-initial-results-with-gnrh-plus-enclomiphene.20864/" target="_blank">have demonstrated</a> that multiple daily manual injections of gonadorelin can function as a replacement for hCG, with other possible benefits. This will not be practical for most, but it absolutely works.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 181512, member: 38109"] This is a garbled interpretation. Gonadorelin is bio-identical to GnRH. Natural men function by producing GnRH pulses for most of their lives. That, in effect, is extremely prolonged use. The kind of "prolonged use" you refer to as causing suppression is actually a continuous infusion of GnRH, rather then the intermittent pulses required by our bodies. This is just something described in research; it's not a treatment. It becomes a treatment intended to cause HPTA suppression when longer-lived GnRH analogs such as triptorelin are used. On the flip side, pulsed doses of gonadorelin are an approved treatment for male hypogonadism; they are proven to normalize the gonadotropins and testosterone. The need for an infusion pump is what limits its appeal. I [URL='https://www.excelmale.com/forum/threads/pituitary-restart-while-on-trt-promising-initial-results-with-gnrh-plus-enclomiphene.20864/']have demonstrated[/URL] that multiple daily manual injections of gonadorelin can function as a replacement for hCG, with other possible benefits. This will not be practical for most, but it absolutely works. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Low progesterone? Frustrated. Thinking of pulling the plug on TRT for good.
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