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Low Fat Vs Low Carb and Weight Loss
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<blockquote data-quote="Nelson Vergel" data-source="post: 197723" data-attributes="member: 3"><p><strong>Low-fat diets and testosterone in men: systematic review and meta-analysis of intervention studies</strong></p><p></p><p>[URL unfurl="true"]https://doi.org/10.1016/j.jsbmb.2021.105878[/URL]</p><p></p><p>Highlights</p><p>•</p><p>Low-fat diets decrease testosterone levels in men</p><p></p><p>•</p><p>Low-fat diets appear to decrease testicular testosterone production</p><p></p><p>•</p><p>Further randomized controlled trials are needed to confirm these effects</p><p></p><p>•</p><p>The effects of low-fat diets on testosterone may differ by ethnicity</p><p></p><p></p><p>Abstract</p><p>Background</p><p>Higher endogenous testosterone levels are associated with reduced chronic disease risk and mortality. Since the mid-20th century, there have been significant changes in dietary patterns, and men’s testosterone levels have declined in western countries. Cross-sectional studies show inconsistent associations between fat intake and testosterone in men.</p><p></p><p>Methods</p><p>Studies eligible for inclusion were intervention studies, with minimal confounding variables, comparing the effect of low-fat vs high-fat diets on men’s sex hormones. 9 databases were searched from their inception to October 2020, yielding 6 eligible studies, with a total of 206 participants. Random effects meta-analyses were performed using Cochrane’s Review Manager software. Cochrane’s risk of bias tool was used for quality assessment.</p><p></p><p>Results</p><p>There were significant decreases in sex hormones on low-fat vs high-fat diets. Standardized mean differences with 95% confidence intervals (CI) for outcomes were: total testosterone [-0.38 (95% CI -0.75 to -0.01) P = 0.04]; free testosterone [-0.37 (95% CI -0.63 to -0.11) P = 0.005]; urinary testosterone [-0.38 (CI 95% -0.66 to -0.09) P = 0.009]; and dihydrotestosterone [-0.3 (CI 95% -0.56 to -0.03) P = 0.03]. There were no significant differences for luteinizing hormone or sex hormone binding globulin. Subgroup analysis for total testosterone, European and North American men, showed a stronger effect [-0.52 (95% CI -0.75 to -0.3) P < 0.001].</p><p></p><p>Conclusions</p><p>Low-fat diets appear to decrease testosterone levels in men, but further randomized controlled trials are needed to confirm this effect. Men with European ancestry may experience a greater decrease in testosterone, in response to a low-fat diet.</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 197723, member: 3"] [B]Low-fat diets and testosterone in men: systematic review and meta-analysis of intervention studies[/B] [URL unfurl="true"]https://doi.org/10.1016/j.jsbmb.2021.105878[/URL] Highlights • Low-fat diets decrease testosterone levels in men • Low-fat diets appear to decrease testicular testosterone production • Further randomized controlled trials are needed to confirm these effects • The effects of low-fat diets on testosterone may differ by ethnicity Abstract Background Higher endogenous testosterone levels are associated with reduced chronic disease risk and mortality. Since the mid-20th century, there have been significant changes in dietary patterns, and men’s testosterone levels have declined in western countries. Cross-sectional studies show inconsistent associations between fat intake and testosterone in men. Methods Studies eligible for inclusion were intervention studies, with minimal confounding variables, comparing the effect of low-fat vs high-fat diets on men’s sex hormones. 9 databases were searched from their inception to October 2020, yielding 6 eligible studies, with a total of 206 participants. Random effects meta-analyses were performed using Cochrane’s Review Manager software. Cochrane’s risk of bias tool was used for quality assessment. Results There were significant decreases in sex hormones on low-fat vs high-fat diets. Standardized mean differences with 95% confidence intervals (CI) for outcomes were: total testosterone [-0.38 (95% CI -0.75 to -0.01) P = 0.04]; free testosterone [-0.37 (95% CI -0.63 to -0.11) P = 0.005]; urinary testosterone [-0.38 (CI 95% -0.66 to -0.09) P = 0.009]; and dihydrotestosterone [-0.3 (CI 95% -0.56 to -0.03) P = 0.03]. There were no significant differences for luteinizing hormone or sex hormone binding globulin. Subgroup analysis for total testosterone, European and North American men, showed a stronger effect [-0.52 (95% CI -0.75 to -0.3) P < 0.001]. Conclusions Low-fat diets appear to decrease testosterone levels in men, but further randomized controlled trials are needed to confirm this effect. Men with European ancestry may experience a greater decrease in testosterone, in response to a low-fat diet. [/QUOTE]
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Low Fat Vs Low Carb and Weight Loss
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