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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Low estradiol with no anastrozole use: Confused.
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<blockquote data-quote="Dr Justin Saya MD" data-source="post: 59391" data-attributes="member: 12687"><p>Yes, unless they have changed, the free estradiol should be the sensitive assay.</p><p></p><p>Per our previous discussions regarding the inexplicable reference change for progesterone at LabCorp, the current progesterone assay is (in my opinion) essentially uninterpretable. For this reason, I've now (effective this week) begun swapping out progesterone for SHBG on routine labs. A slight cost difference for patients (SHBG costs more), but certainly more clinically useful especially given the progesterone assay changes. Progesterone of 0.2 is perfectly normal (for SURE it is not high). For reference just yesterday EVERY SINGLE patient had a progesterone of 0.2 or higher...it is normal but falsely flagged as high due to the abnormally low change to the reference range.</p></blockquote><p></p>
[QUOTE="Dr Justin Saya MD, post: 59391, member: 12687"] Yes, unless they have changed, the free estradiol should be the sensitive assay. Per our previous discussions regarding the inexplicable reference change for progesterone at LabCorp, the current progesterone assay is (in my opinion) essentially uninterpretable. For this reason, I've now (effective this week) begun swapping out progesterone for SHBG on routine labs. A slight cost difference for patients (SHBG costs more), but certainly more clinically useful especially given the progesterone assay changes. Progesterone of 0.2 is perfectly normal (for SURE it is not high). For reference just yesterday EVERY SINGLE patient had a progesterone of 0.2 or higher...it is normal but falsely flagged as high due to the abnormally low change to the reference range. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Low estradiol with no anastrozole use: Confused.
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