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I know I'm a broken record, but Dr. Rouzier prescribes oral estradiol when he feels it would help the men taking testosterone who still aren't doing well.  Injecting it is a different story, perhaps.  This is the flip side of men who take 1 to 3 mg of anastrazole a week, along with T and feel/function better with E2 <5 pg.  For me, I'm an outlier who either needs quite high E2 or E2 in the basement.  My urologist and I are going to hash this out.