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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
Low dose T3 (Cytomel) for fatigue
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<blockquote data-quote="Ardoc2" data-source="post: 138141" data-attributes="member: 35578"><p>I'm posting this for reference and information only but would welcome any insights/comments you all may have.</p><p></p><p>In June of 2018 I had blood work done after visiting my TRT doctor regarding fatigue and trouble sleeping. My sex hormones turned out to still be in the same good range that I had been stable at for quite some time, but as usual we also tested my Thyroid hormones.</p><p>These were my results;</p><p></p><p><u>JUNE 11, 2018</u></p><p>TSH 1.5 mIU/L RANGE: 0.32 - 4.00</p><p>FT3 <strong>2.9 pmol/L</strong> RANGE: 3.1 - 6.2 <strong>LOW</strong> </p><p>FT4 15 pmol/L RANGE: 9 - 19</p><p>rT3 <strong>29 ng/dl</strong> RANGE: 8 - 25 <strong>HIGH</strong></p><p></p><p><u>OCTOBER 3, 2018</u></p><p>TSH 1.21 mIU/L RANGE: 0.32 - 4.00</p><p>FT3 3.6 pmol/L RANGE: 3.1 - 6.2</p><p>FT4 10 pmol/L RANGE: 9 - 19</p><p>rT3 17 ng/dl RANGE: 8 - 25</p><p></p><p><u>DECEMBER 21, 2018</u></p><p>TSH 1.05 mIU/L RANGE: 0.32 - 4.00 </p><p>FT3 3.1 pmol/l RANGE: 2.6 - 5.8 <em>(THIS RANGE WAS CHANGED FROM 3.1 - 6.2 on NOVEMBER 4, 2018?)</em></p><p>FT4 13 pmol/l RANGE: 9 - 19</p><p>rT3 18 ng/dl RANGE: 8 - 25</p><p></p><p>After the June 2018 visit my Dr. started me on 5mcg of Cytomel per day taken in the morning bumping to 10 mcg after one week. I have been on that dose ever since and it has reduced my fatigue and improved my sleep. According to the results above it seems to have corrected (helped to correct?) my high rT3 while leaving my TSH and other values within normal range.</p><p>The FT3 value shown in December still indicates its on the low side but this was 24+ hours after taking my last Cytomel dose. Based on what I have read (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167556/" target="_blank">Single Dose T3 Administration: Kinetics and Effects on Biochemical and Physiologic Parameters</a>) after a single dose of Cytomel, serum concentrations will fall almost to baseline levels after 24 hrs. Meaning this is the lowest level that I should measure over any 24 hour period?</p><p></p><p>I always hear about how virtually any amount of exogenous hormones will completely suppress the endogenous production which does not seem to be the case here? My TSH has fallen but is still well within normal range.</p><p></p><p>Should I test my FT3 a few hours after taking my Cytomel dose just to determine peak value on this protocol?</p><p></p><p>I have also since read about someone on a bodybuilding forum who takes 12.5 mcg ongoing daily with moderate recomp benefits. I have also experienced a subtle, but noticeable improvement in that regard.</p><p></p><p>As thoughts on thyroid hormones and their role in TRT seems to be evolving, I thought some may want to read my experience with low dose cytomel.</p><p></p><p>Any thoughts or comments are welcome.</p></blockquote><p></p>
[QUOTE="Ardoc2, post: 138141, member: 35578"] I'm posting this for reference and information only but would welcome any insights/comments you all may have. In June of 2018 I had blood work done after visiting my TRT doctor regarding fatigue and trouble sleeping. My sex hormones turned out to still be in the same good range that I had been stable at for quite some time, but as usual we also tested my Thyroid hormones. These were my results; [U]JUNE 11, 2018[/U] TSH 1.5 mIU/L RANGE: 0.32 - 4.00 FT3 [B]2.9 pmol/L[/B] RANGE: 3.1 - 6.2 [B]LOW[/B] FT4 15 pmol/L RANGE: 9 - 19 rT3 [B]29 ng/dl[/B] RANGE: 8 - 25 [B]HIGH[/B] [U]OCTOBER 3, 2018[/U] TSH 1.21 mIU/L RANGE: 0.32 - 4.00 FT3 3.6 pmol/L RANGE: 3.1 - 6.2 FT4 10 pmol/L RANGE: 9 - 19 rT3 17 ng/dl RANGE: 8 - 25 [U]DECEMBER 21, 2018[/U] TSH 1.05 mIU/L RANGE: 0.32 - 4.00 FT3 3.1 pmol/l RANGE: 2.6 - 5.8 [I](THIS RANGE WAS CHANGED FROM 3.1 - 6.2 on NOVEMBER 4, 2018?)[/I] FT4 13 pmol/l RANGE: 9 - 19 rT3 18 ng/dl RANGE: 8 - 25 After the June 2018 visit my Dr. started me on 5mcg of Cytomel per day taken in the morning bumping to 10 mcg after one week. I have been on that dose ever since and it has reduced my fatigue and improved my sleep. According to the results above it seems to have corrected (helped to correct?) my high rT3 while leaving my TSH and other values within normal range. The FT3 value shown in December still indicates its on the low side but this was 24+ hours after taking my last Cytomel dose. Based on what I have read ([URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167556/']Single Dose T3 Administration: Kinetics and Effects on Biochemical and Physiologic Parameters[/URL]) after a single dose of Cytomel, serum concentrations will fall almost to baseline levels after 24 hrs. Meaning this is the lowest level that I should measure over any 24 hour period? I always hear about how virtually any amount of exogenous hormones will completely suppress the endogenous production which does not seem to be the case here? My TSH has fallen but is still well within normal range. Should I test my FT3 a few hours after taking my Cytomel dose just to determine peak value on this protocol? I have also since read about someone on a bodybuilding forum who takes 12.5 mcg ongoing daily with moderate recomp benefits. I have also experienced a subtle, but noticeable improvement in that regard. As thoughts on thyroid hormones and their role in TRT seems to be evolving, I thought some may want to read my experience with low dose cytomel. Any thoughts or comments are welcome. [/QUOTE]
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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
Low dose T3 (Cytomel) for fatigue
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