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You may be talking about the honeymoon phase of TRT and not low cortisol. I also have low cortisol issues. For me, it’s been a challenge, but the things that have worked best were figuring out different schemes of pregnenolone, T3 and T4, rhodiola, and potentially using cortisone acetate or adrenal glandulars. Playing with your T dose and form can also help.


It’s also possible that it’s more of a cortisol regulation issue than low cortisol, which is a theory of mine based on me extensive experience trying things out over time. Cortisol has active and inactive forms, and it’s possible that in some people like maybe me that your body shifts more to run on the active forms, which has negative effects, and has less inactive forms to transport it where it needs to be, which also has negative effects.


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