Long-Term Testosterone Therapy Reduces Risk of Cardiovascular Disease

Jinzang

Member
Full text of a journal article published on February 9th. Here is a brief excerpt:

In this report, we present data from an observational registry study on Testosterone Therapy (TTh). in 360 men with hypogonadism who were followed up for a period of 8 years while on continuous TTh and compared these findings to data from 296 men with hypogonadism who remained untreated for the same follow-up period, approaching 8 years. Of particular interest is that there were only 2 deaths in the T-treated group and none was related to CV events. Interestingly, in the nontreated control group, there were 21 deaths, 19 of which were related to CV events. Furthermore, there were 26 nonfatal MIs and 30 nonfatal strokes in the control group but none in the T-treated group. These findings are in agreement with prior observational studies.

In this study every measure of health they took improved in the TTh group. A very positive result.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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