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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Lipoderm Gel - Scrotal
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<blockquote data-quote="madman" data-source="post: 199311" data-attributes="member: 13851"><p>Of course!</p><p></p><p></p><p>[URL unfurl="true"]https://www.defymedical.com/home/mens-health-overview/testosterone-replacement-therapy/testosterone-topical-cream/[/URL]</p><p></p><p><strong>The Benefits of Compounded Medications</strong></p><p></p><p>Using compounded transdermal testosterone appears to be more effective than the brand name (manufactured) transdermal testosterone products (Androgel, Testim, etc.) for a few reasons.</p><ul> <li data-xf-list-type="ul">Higher concentrations of testosterone can be achieved in a compounded transdermal.</li> <li data-xf-list-type="ul">Most male patients respond best to dosages between 5% - 20% applied topically to reach 5mg-10mg absorption.</li> <li data-xf-list-type="ul"><ul> <li data-xf-list-type="ul">Common strengths found in compounded topical testosterone products range between 5%-20% testosterone. 5% equals a 50mg/ml concentration of testosterone; 7% equals 70mg/ml; 10% equals 100mg/ml; etc.</li> <li data-xf-list-type="ul">The highest concentration available for most transdermal hormone creams and gels is 20% or 200mg/ml. More than 20% concentration may result in a poor distribution of the testosterone, ‘clumping’ of the ingredients, and reduced absorption of the medication.</li> </ul></li> <li data-xf-list-type="ul">Patients can select the transdermal delivery system that works best for them through compounding.<ul> <li data-xf-list-type="ul"><strong><em><u>For example, cream-based delivery systems apply better to skin in sensitive areas, such as the scrotum or inner thighs</u>. Using an alcohol-based gel in these areas can irritate the skin, therefore using a compounded cream is preferred.</em></strong></li> <li data-xf-list-type="ul">Some patients who do not experience skin irritation may like the consistency and faster rate of absorption found in gels. Compounding pharmacies can compound either a gel or cream depending on what the prescription calls for. If the type of delivery system is not specified on the prescription, the pharmacy will usually default to either a cream or gel base.</li> </ul></li> </ul><p></p><p></p><p></p><p></p><p><strong>Available Transdermal Delivery Systems for Testosterone</strong></p><p><strong></strong></p><p><strong>Compounded Medications</strong></p><p></p><p>Testosterone is available at compounding pharmacies that specialize in hormone preparations.</p><p></p><p><strong><em>Compounding pharmacies have the ability to customize topically applied testosterone into different strengths and combinations using a variety of transdermal delivery systems (Lipoderm, HRT, Versabase, alcohol gel).</em></strong></p><p></p><p>Compounding pharmacies can be used to prescribe a higher concentrated transdermal testosterone which will allow enough of the hormone to be absorbed to maintain a good physiologic level of total testosterone.</p><p></p><p><strong><em>In addition, testosterone can be compounded using a custom delivery system which will result in minimal skin reactions. Lipoderm, Versabase, and HRT base are delivery systems that can provide maximum bioavailability and penetration of active ingredients while minimizing skin irritation that can occur with alcohol-based gels or transdermal patches.</em></strong></p><p></p><p>The higher dose compounded testosterone creams containing 5% to 20% testosterone have been available by physician’s prescription from any compounding pharmacy specializing in hormone preparations.</p><p></p><p>The cost for compounded testosterone creams is less than 1% AndroGel® and less expensive generic alternatives can be compounded by many pharmacists. Low-dose dihydrotestosterone, DHT gel, labeled Andactrim™, also from Solvay, has been available in Europe for almost a decade. Doctors who specialize in bio-identical hormone replacement therapy have been using cream and gel delivery of female hormones for decades.</p><p></p><p>Compounded testosterone creams create more physiologic testosterone levels, skin reactions are minimal, and short-term discontinuation of therapy is possible due to the longer half-life of up to 25 hours.</p><p></p><p><em><strong>Scrotal application is also convenient and discrete while theoretically producing more DHT than when applied to other locations on the body.</strong></em></p></blockquote><p></p>
[QUOTE="madman, post: 199311, member: 13851"] Of course! [URL unfurl="true"]https://www.defymedical.com/home/mens-health-overview/testosterone-replacement-therapy/testosterone-topical-cream/[/URL] [B]The Benefits of Compounded Medications[/B] Using compounded transdermal testosterone appears to be more effective than the brand name (manufactured) transdermal testosterone products (Androgel, Testim, etc.) for a few reasons. [LIST] [*]Higher concentrations of testosterone can be achieved in a compounded transdermal. [*]Most male patients respond best to dosages between 5% - 20% applied topically to reach 5mg-10mg absorption. [*] [LIST] [*]Common strengths found in compounded topical testosterone products range between 5%-20% testosterone. 5% equals a 50mg/ml concentration of testosterone; 7% equals 70mg/ml; 10% equals 100mg/ml; etc. [*]The highest concentration available for most transdermal hormone creams and gels is 20% or 200mg/ml. More than 20% concentration may result in a poor distribution of the testosterone, ‘clumping’ of the ingredients, and reduced absorption of the medication. [/LIST] [*]Patients can select the transdermal delivery system that works best for them through compounding. [LIST] [*][B][I][U]For example, cream-based delivery systems apply better to skin in sensitive areas, such as the scrotum or inner thighs[/U]. Using an alcohol-based gel in these areas can irritate the skin, therefore using a compounded cream is preferred.[/I][/B] [*]Some patients who do not experience skin irritation may like the consistency and faster rate of absorption found in gels. Compounding pharmacies can compound either a gel or cream depending on what the prescription calls for. If the type of delivery system is not specified on the prescription, the pharmacy will usually default to either a cream or gel base. [/LIST] [/LIST] [B]Available Transdermal Delivery Systems for Testosterone Compounded Medications[/B] Testosterone is available at compounding pharmacies that specialize in hormone preparations. [B][I]Compounding pharmacies have the ability to customize topically applied testosterone into different strengths and combinations using a variety of transdermal delivery systems (Lipoderm, HRT, Versabase, alcohol gel).[/I][/B] Compounding pharmacies can be used to prescribe a higher concentrated transdermal testosterone which will allow enough of the hormone to be absorbed to maintain a good physiologic level of total testosterone. [B][I]In addition, testosterone can be compounded using a custom delivery system which will result in minimal skin reactions. Lipoderm, Versabase, and HRT base are delivery systems that can provide maximum bioavailability and penetration of active ingredients while minimizing skin irritation that can occur with alcohol-based gels or transdermal patches.[/I][/B] The higher dose compounded testosterone creams containing 5% to 20% testosterone have been available by physician’s prescription from any compounding pharmacy specializing in hormone preparations. The cost for compounded testosterone creams is less than 1% AndroGel® and less expensive generic alternatives can be compounded by many pharmacists. Low-dose dihydrotestosterone, DHT gel, labeled Andactrim™, also from Solvay, has been available in Europe for almost a decade. Doctors who specialize in bio-identical hormone replacement therapy have been using cream and gel delivery of female hormones for decades. Compounded testosterone creams create more physiologic testosterone levels, skin reactions are minimal, and short-term discontinuation of therapy is possible due to the longer half-life of up to 25 hours. [I][B]Scrotal application is also convenient and discrete while theoretically producing more DHT than when applied to other locations on the body.[/B][/I] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Lipoderm Gel - Scrotal
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