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That's basically argument from authority. They may simply be responding to the demands of their customers, who by and large have more-is-better thinking. I see that [USER=38668]@Willyt[/USER] has already mentioned Xyosted. Its success dispels the notion that supra-physiological doses are needed to ameliorate symptoms of hypogonadism. The main thing I object to is starting new patients on 100+ mg TC/week when many will be harmed by this practice.

There is an evolution-based argument in favor of targeting average serum levels for healthy young men, which can be the 600-700 ng/dL figure of earlier decades, predating the recent decline. The reasoning is that nature had selected those levels as optimal for reproductive success. Reproductive success is then suggested to be a decent proxy for overall success in life; you have the resources and skills to attract a mate and ensure the survival of the resulting offspring. So in the end this gets you back to those physiological doses of testosterone, around 3-9 mg/day.