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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Left ventricle Hypertrophy
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<blockquote data-quote="xqfq" data-source="post: 165185" data-attributes="member: 38167"><p>Based on the Tru-T.org calculator, at your trough your free T is 30.08 ng/dL, with the theraputic range listed as 16-31 ng/dl. Filling in the blanks and assuming a 100 ng/dL-per day drop off and a once-a-week injection schedule, <strong>your peak total T could be 1422 ng/dL, with a free T (tru-t.org calculator) of 53.63 ng/dL.</strong></p><p></p><p>So your dosage / injection schedule may be leaving you too high, or too high for your body. You may have room to reduce your dosage. <strong>You may want to discuss reducing your dose and increasing your injection frequency with your doctor, e.g. 3 times a week or every other day using a small insulin syringe. There are many threads on this forum about this - lots of good information.</strong></p><p></p><p>Like 'free T', there is also 'free E2'. But it's harder to calculate. Using one spreadsheet, you free E2 at trough could be something like 0.8 pg/mL. According to <a href="https://www.discountedlabs.com/free-estradiol-sensitive" target="_blank">Free Estradiol (Sensitive)</a>, the range for this might be 0.2 - 1.5 pg/mL in adult men. At your estimated peak of 1422 ng/dL total testosterone, your free E2 is likely <em>well</em> above the range as well. But I am not sure what the 'rule of thumb' for E2 increase with total T is, so I'd only be guessing here.</p><p></p><p>---</p><p></p><p>If you injected more frequently, say every day or every other day, it would be more easy to know where your numbers are because they would be more constant.</p><p></p><p>---</p><p></p><p>General tips for hypertension:</p><p></p><p>There are many lifestyle changes you can make that may reduce your hypertension. Here's a short video: [MEDIA=youtube]hT18-qwt_hQ[/MEDIA]</p><p></p><p>What I have heard works well:</p><p></p><p> * Increased magnesium - 400mg - 800mg/day, supplements usually needed. I take magnesium citrate 3x a day.</p><p> * Hit RDA of potassium, which is 4700mg/day.</p><p> * Potentially decrease sodium intake.</p><p> * Cardiovascular exercise.</p><p> * Improve sleep hygiene.</p><p></p><p>It's important to talk with your doctor before doing any of these (especially, IMO, the exercise)</p><p></p><p>But because I am guessing your hypertension didn't start until TRT, it's probably "secondary" to some effect of your TRT. Which is why it might make sense to increase your injection frequency and lower your dose.</p><p></p><p>Many people are apprehensive about taking blood pressure medication. If I was in your shoes, I would personally take any medication, have my blood pressure return to the healthy range, and then investigate underlying causes. For many, high blood pressure has no known cause. The good news is that there are many medications available to treat blood pressure, and they are cheap.</p><p></p><p>---</p><p></p><p>Please keep in mind that this is serious stuff, I'm not a doctor, and I'm just giving you my opinions here. I hope you can try and talk with Dr. Thomas O'Connor - I know he knows his stuff here.</p></blockquote><p></p>
[QUOTE="xqfq, post: 165185, member: 38167"] Based on the Tru-T.org calculator, at your trough your free T is 30.08 ng/dL, with the theraputic range listed as 16-31 ng/dl. Filling in the blanks and assuming a 100 ng/dL-per day drop off and a once-a-week injection schedule, [B]your peak total T could be 1422 ng/dL, with a free T (tru-t.org calculator) of 53.63 ng/dL.[/B] So your dosage / injection schedule may be leaving you too high, or too high for your body. You may have room to reduce your dosage. [B]You may want to discuss reducing your dose and increasing your injection frequency with your doctor, e.g. 3 times a week or every other day using a small insulin syringe. There are many threads on this forum about this - lots of good information.[/B] Like 'free T', there is also 'free E2'. But it's harder to calculate. Using one spreadsheet, you free E2 at trough could be something like 0.8 pg/mL. According to [URL='https://www.discountedlabs.com/free-estradiol-sensitive']Free Estradiol (Sensitive)[/URL], the range for this might be 0.2 - 1.5 pg/mL in adult men. At your estimated peak of 1422 ng/dL total testosterone, your free E2 is likely [I]well[/I] above the range as well. But I am not sure what the 'rule of thumb' for E2 increase with total T is, so I'd only be guessing here. --- If you injected more frequently, say every day or every other day, it would be more easy to know where your numbers are because they would be more constant. --- General tips for hypertension: There are many lifestyle changes you can make that may reduce your hypertension. Here's a short video: [MEDIA=youtube]hT18-qwt_hQ[/MEDIA] What I have heard works well: * Increased magnesium - 400mg - 800mg/day, supplements usually needed. I take magnesium citrate 3x a day. * Hit RDA of potassium, which is 4700mg/day. * Potentially decrease sodium intake. * Cardiovascular exercise. * Improve sleep hygiene. It's important to talk with your doctor before doing any of these (especially, IMO, the exercise) But because I am guessing your hypertension didn't start until TRT, it's probably "secondary" to some effect of your TRT. Which is why it might make sense to increase your injection frequency and lower your dose. Many people are apprehensive about taking blood pressure medication. If I was in your shoes, I would personally take any medication, have my blood pressure return to the healthy range, and then investigate underlying causes. For many, high blood pressure has no known cause. The good news is that there are many medications available to treat blood pressure, and they are cheap. --- Please keep in mind that this is serious stuff, I'm not a doctor, and I'm just giving you my opinions here. I hope you can try and talk with Dr. Thomas O'Connor - I know he knows his stuff here. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Left ventricle Hypertrophy
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