LC/MS vs immunoassay

LiveX2

Member
My doctor wrote lab scripts for TT, FT, PSA, FSH, estradiol, prolactin, and some others. I think the LC/MS is the preferred test to get an accurate measure of TT (or something like that). For the T script, he ordered # 873 (quest lab immunoassay).

Should I ask that he update the order for # 15983 (LC/S-MS)? and
If I was not on nandrolone + T, would it matter what test he orders?

 
My doctor wrote lab scripts for TT, FT, PSA, FSH, estradiol, prolactin, and some others. I think the LC/MS is the preferred test to get an accurate measure of TT (or something like that). For the T script, he ordered # 873 (quest lab immunoassay).

Should I ask that he update the order for # 15983 (LC/S-MS)? and
If I was not on nandrolone + T, would it matter what test he orders?


You would need to use the most accurate assays, TT (LC/MS-MS) and Free Testosterone (Equilibrium Dialysis or Ultrafiltration), especially when using ND as part of a protocol otherwise your results will be skewed.

These are the assays needed when testing TT/FT.

Both assays are critical and need to be used when adding nandrolone to a T-only protocol.

Most would use Labcorps TT (LC/MS-MS)/FT (Equilibrium Ultrafiltration) or Quest Diagnostics TT (LC/MS-MS)/FT (Equilibrium Dialysis).

When testing your FT either one will suffice!




Labcorp

1. 500726: Testosterone, Free, Mass Spectrometry/Equilibrium Dialysis (Endocrine Sciences) | Labcorp

2. 070038: Testosterone, Free, Equilibrium Ultrafiltration With Total Testosterone, LC/MS-MS | Labcorp


Quest Diagnostics

1. Testosterone, Total, LC/MS, and Free (Equilibrium Dialysis)




If you prefer Quest over Labcorp then this is the test panel Quest Diagnostics: Test Directory you want.

Better yet you can order through Nelson's discounted labs link posted above under Quest Diagnostics.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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