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Health & Wellness
Latest Update on Metformin
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<blockquote data-quote="Nelson Vergel" data-source="post: 79202" data-attributes="member: 3"><p>Warning:</p><p></p><p>Metformin decreases B-12 and citrulline. Supplement both!</p><p></p><p>It also decreases testosterone in men not on TRT. It decreases IGF-1 also.</p><p></p><p>I lost weight but also some muscle and the some of the "pump" at the gym.</p><p></p><p>The most striking and unexpected thing for me was the improvement in my bloating and irritable bowel syndrome. This is counterintuitive since diarrhea may be experienced in some people on metformin. I take a low dose of 500 mg twice per day with food (I had normal blood sugar to start with). The biggest antiaging study in history is using 850 mg twice per day. Not sure if I will attempt to go up in dose.</p><p></p><p>I started supplementing 5000 mg per day of citrulline and the pump is back but my bloat is slightly back at about 50% of what it used to be prior to metformin.</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 79202, member: 3"] Warning: Metformin decreases B-12 and citrulline. Supplement both! It also decreases testosterone in men not on TRT. It decreases IGF-1 also. I lost weight but also some muscle and the some of the "pump" at the gym. The most striking and unexpected thing for me was the improvement in my bloating and irritable bowel syndrome. This is counterintuitive since diarrhea may be experienced in some people on metformin. I take a low dose of 500 mg twice per day with food (I had normal blood sugar to start with). The biggest antiaging study in history is using 850 mg twice per day. Not sure if I will attempt to go up in dose. I started supplementing 5000 mg per day of citrulline and the pump is back but my bloat is slightly back at about 50% of what it used to be prior to metformin. [/QUOTE]
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General Health & Fitness
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Latest Update on Metformin
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