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Latest Update on Metformin
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<blockquote data-quote="Nelson Vergel" data-source="post: 61208" data-attributes="member: 3"><p><strong>Consider Metformin in Patients with These Comorbidities</strong></p><p></p><p>Ann Intern Med; ePub 2017 Jan 3; Crowley, et al</p><p></p><p>January 20, 2017</p><p></p><p>Using metformin in patients with diabetes and moderate chronic kidney or liver disease, or heart failure, is linked with improved outcomes, according to a systematic review involving 17 observational studies.</p><p></p><p>Investigators looked at studies that 1) examined adults with type 2 diabetes and CKD (chronic kidney failure), CHF (chronic heart failure), or CLD (chronic liver disease) with hepatic impairment; 2) compared treatments that did and did not include metformin; and 3) analyzed all-cause mortality, adverse CV events, and other outcomes. Among the results:</p><p></p><p>Metformin led to a reduction in all-cause mortality in patients with CKD, CHF, or CLD with hepatic impairment.</p><p>It also caused fewer heart failure readmissions in patients with CKD or CHF.</p><p></p><p>The authors concluded that their findings support changes made recently in metformin labeling.</p><p></p><p><a href="http://www.mdedge.com/clinicalendocrinologynews/clinical-edge/summary/diabetes/consider-metformin-patients-these?ce_stack=5251&utm_source=PANTHEON_STRIPPED&utm_medium=PANTHEON_STRIPPED&utm_content=PANTHEON_STRIPPED&Comorbidities_|_Treating_Transgender_Patients_|_=&More_ClinicalEdge=" target="_blank">http://www.mdedge.com/clinicalendocrinologynews/clinical-edge/summary/diabetes/consider-metformin-patients-these?ce_stack=5251&utm_source=PANTHEON_STRIPPED&utm_medium=PANTHEON_STRIPPED&utm_content=PANTHEON_STRIPPED&Comorbidities_|_Treating_Transgender_Patients_|_=&More_ClinicalEdge=</a></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 61208, member: 3"] [B]Consider Metformin in Patients with These Comorbidities[/B] Ann Intern Med; ePub 2017 Jan 3; Crowley, et al January 20, 2017 Using metformin in patients with diabetes and moderate chronic kidney or liver disease, or heart failure, is linked with improved outcomes, according to a systematic review involving 17 observational studies. Investigators looked at studies that 1) examined adults with type 2 diabetes and CKD (chronic kidney failure), CHF (chronic heart failure), or CLD (chronic liver disease) with hepatic impairment; 2) compared treatments that did and did not include metformin; and 3) analyzed all-cause mortality, adverse CV events, and other outcomes. Among the results: Metformin led to a reduction in all-cause mortality in patients with CKD, CHF, or CLD with hepatic impairment. It also caused fewer heart failure readmissions in patients with CKD or CHF. The authors concluded that their findings support changes made recently in metformin labeling. [url]http://www.mdedge.com/clinicalendocrinologynews/clinical-edge/summary/diabetes/consider-metformin-patients-these?ce_stack=5251&utm_source=PANTHEON_STRIPPED&utm_medium=PANTHEON_STRIPPED&utm_content=PANTHEON_STRIPPED&Comorbidities_|_Treating_Transgender_Patients_|_=&More_ClinicalEdge=[/url] [/QUOTE]
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Latest Update on Metformin
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