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Latest Update on Metformin
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<blockquote data-quote="Vince" data-source="post: 241398" data-attributes="member: 843"><p>Anyway, open-access full-text & PDF is available for the paper at AHA Stroke:</p><p><a href="http://stroke.ahajournals.org/content/early/2017/04/20/STROKEAHA.116.016027" target="_blank">Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia</a></p><p></p><p>They apparently did not segregate the data by artificial sweetener type (and probably couldn't, being a recall survey):</p><p><em>Artificially sweetened beverages are typically sweetened with non-nutritive sweeteners, such as saccharin, acesulfame, aspartame, neotame, or sucralose. At the time of FFQ administration in this study, saccharin, acesulfame-K, and aspartame were Food and Drug Administration approved, whereas sucralose was approved in 1999, neotame in 2002, and stevia in 2008.</em></p><p></p><p>Stevia is not "artificial", but it's also non-factor in this data set for sweetened beverages, and has only round-off-error market share even today.</p><p></p><p>The shift away from aspartame could be just demand-based, or driven by focus panel results, but I wouldn't rule out some fire below that particular smoke signal.</p><p></p><p>Any canned or bottled beverage has other confounders as well. Perhaps the biggest is what water they use, and that varies by both bottling plant and licensed formulation terms. Municipal water is at high risk of containing chloramine, which may actually be more adverse to gut flora than either sugar or artificial sweeteners.</p><p></p><p>We lately discovered that the bagged ice we buy is not only from a muni water source, but the ice maker <strong><em>adds</em></strong> more chloramine to it. How's that credit card commercial go?</p><p>What's in <em>your</em> water?</p></blockquote><p></p>
[QUOTE="Vince, post: 241398, member: 843"] Anyway, open-access full-text & PDF is available for the paper at AHA Stroke: [URL='http://stroke.ahajournals.org/content/early/2017/04/20/STROKEAHA.116.016027']Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia[/URL] They apparently did not segregate the data by artificial sweetener type (and probably couldn't, being a recall survey): [I]Artificially sweetened beverages are typically sweetened with non-nutritive sweeteners, such as saccharin, acesulfame, aspartame, neotame, or sucralose. At the time of FFQ administration in this study, saccharin, acesulfame-K, and aspartame were Food and Drug Administration approved, whereas sucralose was approved in 1999, neotame in 2002, and stevia in 2008.[/I] Stevia is not "artificial", but it's also non-factor in this data set for sweetened beverages, and has only round-off-error market share even today. The shift away from aspartame could be just demand-based, or driven by focus panel results, but I wouldn't rule out some fire below that particular smoke signal. Any canned or bottled beverage has other confounders as well. Perhaps the biggest is what water they use, and that varies by both bottling plant and licensed formulation terms. Municipal water is at high risk of containing chloramine, which may actually be more adverse to gut flora than either sugar or artificial sweeteners. We lately discovered that the bagged ice we buy is not only from a muni water source, but the ice maker [B][I]adds[/I][/B] more chloramine to it. How's that credit card commercial go? What's in [I]your[/I] water? [/QUOTE]
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Latest Update on Metformin
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