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Latest Update on Metformin
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<blockquote data-quote="mcs" data-source="post: 238729" data-attributes="member: 12"><p style="text-align: center"><span style="font-size: 18px">Observations being on ER-Metformin for last 4.5 mos.</span></p> <p style="text-align: center"><span style="font-size: 12px">(started July 1, 2022)</span></p> <ol> <li data-xf-list-type="ol"><strong><span style="font-size: 15px"><strong> 15lbs weight loss - </strong></span></strong><span style="font-size: 15px">no change in diet or training</span></li> <li data-xf-list-type="ol"><strong><span style="font-size: 15px"><strong> No GI problems up to 2g/day</strong></span></strong></li> <li data-xf-list-type="ol"><strong><span style="font-size: 15px"><strong> No change in fasting glucose levels or a1c </strong></span></strong><span style="font-size: 15px">(not diabetic to begin with)</span></li> <li data-xf-list-type="ol"><span style="font-size: 15px"><strong> *Substantial decrease in total and free T (not on TRT):</strong><br /> <ul> <li data-xf-list-type="ul"><span style="font-size: 15px">June, 2022 (pre-Metformin): TT: 553; FT: 76.9</span></li> <li data-xf-list-type="ul"><span style="font-size: 15px">August, 2022 (1 month Metformin): TT: 415; FT: 70.2</span></li> <li data-xf-list-type="ul"><span style="font-size: 15px">November, 2022 (4 months Metformin): TT: 318; FT: 61.7</span></li> </ul></span></li> <li data-xf-list-type="ol"><strong><span style="font-size: 15px"><strong> No difference in aerobic or resistance training </strong></span></strong></li> <li data-xf-list-type="ol"><strong><span style="font-size: 15px"><strong> Slight decrease in IGF-1 </strong></span></strong><span style="font-size: 15px">(which I don't mind because mine was already high normal @ 250)</span></li> <li data-xf-list-type="ol"><strong><span style="font-size: 15px"><strong> B12 is still over range</strong></span></strong><span style="font-size: 15px"> (because I supplement with 1-2mg/day!)</span></li> </ol><p><span style="font-size: 15px">*I was always on the fence about TRT but now since the Metformin has tanked my levels, maybe this is the push I need? The only problem is I have hypertension and had clotting issues in the past, both of which I'm managing with meds (telmisartan, nebivolol, rivaroxaban), but the hypertension is on the top of my list of TRT side effects and BP is still not where I'd like to see it (120/80 or less). 62 y/o male.</span></p><p><span style="font-size: 15px"></span></p><p><span style="font-size: 15px">Thoughts?</span></p></blockquote><p></p>
[QUOTE="mcs, post: 238729, member: 12"] [CENTER][SIZE=18px]Observations being on ER-Metformin for last 4.5 mos.[/SIZE] [SIZE=12px](started July 1, 2022)[/SIZE][/CENTER] [LIST=1] [*][B][SIZE=15px][B] 15lbs weight loss - [/B][/SIZE][/B][SIZE=15px]no change in diet or training[/SIZE] [*][B][SIZE=15px][B] No GI problems up to 2g/day[/B][/SIZE][/B] [*][B][SIZE=15px][B] No change in fasting glucose levels or a1c [/B][/SIZE][/B][SIZE=15px](not diabetic to begin with)[/SIZE] [*][SIZE=15px][B] *Substantial decrease in total and free T (not on TRT):[/B] [LIST] [*][SIZE=15px]June, 2022 (pre-Metformin): TT: 553; FT: 76.9[/SIZE] [*][SIZE=15px]August, 2022 (1 month Metformin): TT: 415; FT: 70.2[/SIZE] [*][SIZE=15px]November, 2022 (4 months Metformin): TT: 318; FT: 61.7[/SIZE] [/LIST][/SIZE] [*][B][SIZE=15px][B] No difference in aerobic or resistance training [/B][/SIZE][/B] [*][B][SIZE=15px][B] Slight decrease in IGF-1 [/B][/SIZE][/B][SIZE=15px](which I don't mind because mine was already high normal @ 250)[/SIZE] [*][B][SIZE=15px][B] B12 is still over range[/B][/SIZE][/B][SIZE=15px] (because I supplement with 1-2mg/day!)[/SIZE] [/LIST] [SIZE=15px]*I was always on the fence about TRT but now since the Metformin has tanked my levels, maybe this is the push I need? The only problem is I have hypertension and had clotting issues in the past, both of which I'm managing with meds (telmisartan, nebivolol, rivaroxaban), but the hypertension is on the top of my list of TRT side effects and BP is still not where I'd like to see it (120/80 or less). 62 y/o male. Thoughts?[/SIZE] [/QUOTE]
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Latest Update on Metformin
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