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I have been following the same protocol for the last 12 months: 70 mg Test Cypionate twice weekly; 500 IU hCG twice weekly; 0.1 mg Anastrozole daily.  I run blood tests just prior to the next injection cycle.


TOTAL TESTOSTERONE


1204 ng/dL LabCorp (Immunoassay 264-916) April 24


1891 ng/dL Quest (LC/MS/MS 250-1100) June 25


FREE TESTOSTERONE 


>50 pg/mL LabCorp (Direct Immunoassay 6.6-18.1) April 24


548.2 pg/mL Quest (Dialysis) 35-155) June 25


E2, SENSITIVE


29.7 pg/mL LabCorp (LC/MS/MS 8-35) April 24


67 pg/mL Quest (LC/MS/MS) June 25


I fully understand that there is no correlation between free Testosterone Direct and free Testosterone by Dialysis, as they have completely different reference ranges. In fact, Direct Immunoassay fT has been completed discredited over the last 20 years.  William Rosner wrote a scathing Letter to the Editor (July 2001, Journal of Endocrinology and Metabolism) entitled, “An Extraordinarily Inaccurate Assay for Free Testosterone is Still with Us”.  He cited the work of Vermeulen and others demonstrating that Direct Immunoassay fT “is seriously inaccurate, underestimating its concentration by many-fold”.


But I do not understand why there is such a big difference between LabCorp’s and Quest’s Total Testosterone.  Perhaps Nelson can offer his words of wisdom.


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