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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Lab Work - What to Track in the Future?
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<blockquote data-quote="madman" data-source="post: 143782" data-attributes="member: 13851"><p><strong>COMPARISON OF TESTOSTERONE, DIHYDROTESTOSTERONE, LUTEINIZING HORMONE, AND FOLLICLE-STIMULATING HORMONE IN SERUM AFTER INJECTION OF TESTOSTERONE ENANTHATE OR TESTOSTERONE CYPIONATE </strong></p><p></p><p></p><p></p><p></p><p>They are basically interchangeable!</p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p>However, since no comparison of the serum testosterone levels achieved by injection of testosterone enanthate or cypionate in equivalent doses has been reported, <strong><span style="color: rgb(184, 49, 47)">it is undecided which of the two esters produces the longer-lasting effects and the more favorable plasma testosterone pattern. </span></strong>To perform this comparison, we analyzed serum testosterone, dihydrotestosterone (DHT), luteinizing hormone (LH), and follicle-stimulating hormone (FSH) concentrations after injection of equal amounts of testosterone given either as enanthate or cypionate to normal men.</p><p></p><p></p><p></p><p></p><p></p><p><strong>Protocol.</strong> The study was designed as a crossover study, so that three subjects first received testosterone enanthate, followed 7 weeks later by testosterone cypionate (cyclopentyl propionate). The other three subjects received testosterone cypionate first, and 7 weeks later testosterone enanthate. On the day prior to injection and on the day of the injection blood samples were collected for baseline determinations. <strong><span style="color: rgb(184, 49, 47)">Blood samples were obtained daily up to day 6 after the injections and every 2nd day from day 6 to day 26. They were always collected between 12 noon and 1 P.M.</span></strong> The serum was stored at - 20° C prior to analysis.</p><p></p><p></p><p></p><p><strong>Testosterone Preparations.</strong> Commercially available testosterone preparations were used. Testosterone enanthate (194 mg) (Schering AG, Berlin! Bergkamen) and testosterone cypionate (200 mg) (Upjohn Co., Kalamazoo, Mich.) <strong><span style="color: rgb(184, 49, 47)">were injected so that the amount of unesterified testosterone was the same in both preparations (140 mg).</span></strong></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p><strong>RESULTS </strong></p><p><strong>Figure 1 shows the serum hormone levels in six normal men after intramuscular injection of either testosterone enanthate or cypionate.</strong> <strong><span style="color: rgb(184, 49, 47)">The serum testosterone profiles were identical after both preparations. </span>The concentrations increased sharply, reaching maximal levels 3 times above basal on days 1 and 2 after injection, and decreased gradually thereafter, so that basal levels were reached on day 10.</strong> Values continued to fall below basal concentrations on days 12 and 14 (P < 0.05) and then returned to basal. DHT showed a significant elevation above basal levels on days 1 to 5. LH concentrations after injection were significantly (P < 0.05) suppressed until day 10. LH levels then began to increase while testosterone levels were still below basal. FSH levels were already below basal on day 1 and remained significantly (P < 0.01) suppressed until day 14. The lowest concentrations were found between days 6 and 10. <strong>The serum profiles of hormones measured in this study, achieved after the administration of either <span style="color: rgb(184, 49, 47)">testosterone enanthate</span> or <span style="color: rgb(184, 49, 47)">cypionate, were at no point significantly different from each other.</span></strong></p></blockquote><p></p>
[QUOTE="madman, post: 143782, member: 13851"] [B]COMPARISON OF TESTOSTERONE, DIHYDROTESTOSTERONE, LUTEINIZING HORMONE, AND FOLLICLE-STIMULATING HORMONE IN SERUM AFTER INJECTION OF TESTOSTERONE ENANTHATE OR TESTOSTERONE CYPIONATE [/B] They are basically interchangeable! However, since no comparison of the serum testosterone levels achieved by injection of testosterone enanthate or cypionate in equivalent doses has been reported, [B][COLOR=rgb(184, 49, 47)]it is undecided which of the two esters produces the longer-lasting effects and the more favorable plasma testosterone pattern. [/COLOR][/B]To perform this comparison, we analyzed serum testosterone, dihydrotestosterone (DHT), luteinizing hormone (LH), and follicle-stimulating hormone (FSH) concentrations after injection of equal amounts of testosterone given either as enanthate or cypionate to normal men. [B]Protocol.[/B] The study was designed as a crossover study, so that three subjects first received testosterone enanthate, followed 7 weeks later by testosterone cypionate (cyclopentyl propionate). The other three subjects received testosterone cypionate first, and 7 weeks later testosterone enanthate. On the day prior to injection and on the day of the injection blood samples were collected for baseline determinations. [B][COLOR=rgb(184, 49, 47)]Blood samples were obtained daily up to day 6 after the injections and every 2nd day from day 6 to day 26. They were always collected between 12 noon and 1 P.M.[/COLOR][/B] The serum was stored at - 20° C prior to analysis. [B]Testosterone Preparations.[/B] Commercially available testosterone preparations were used. Testosterone enanthate (194 mg) (Schering AG, Berlin! Bergkamen) and testosterone cypionate (200 mg) (Upjohn Co., Kalamazoo, Mich.) [B][COLOR=rgb(184, 49, 47)]were injected so that the amount of unesterified testosterone was the same in both preparations (140 mg).[/COLOR][/B] [B]RESULTS Figure 1 shows the serum hormone levels in six normal men after intramuscular injection of either testosterone enanthate or cypionate.[/B] [B][COLOR=rgb(184, 49, 47)]The serum testosterone profiles were identical after both preparations. [/COLOR]The concentrations increased sharply, reaching maximal levels 3 times above basal on days 1 and 2 after injection, and decreased gradually thereafter, so that basal levels were reached on day 10.[/B] Values continued to fall below basal concentrations on days 12 and 14 (P < 0.05) and then returned to basal. DHT showed a significant elevation above basal levels on days 1 to 5. LH concentrations after injection were significantly (P < 0.05) suppressed until day 10. LH levels then began to increase while testosterone levels were still below basal. FSH levels were already below basal on day 1 and remained significantly (P < 0.01) suppressed until day 14. The lowest concentrations were found between days 6 and 10. [B]The serum profiles of hormones measured in this study, achieved after the administration of either [COLOR=rgb(184, 49, 47)]testosterone enanthate[/COLOR] or [COLOR=rgb(184, 49, 47)]cypionate, were at no point significantly different from each other.[/COLOR][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Lab Work - What to Track in the Future?
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