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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Lab results. Diagnosing ED/Libido
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<blockquote data-quote="madman" data-source="post: 170188" data-attributes="member: 13851"><p>You are Canadian as I can tell you had your blood work done at Lifelabs.</p><p></p><p>How long have you been on said protocol?.....<span style="color: rgb(184, 49, 47)">200mg test E and 1mg adex, split into twice weekly doses. I pin sub Q Mon nights and Fri mornings.</span></p><p></p><p>What was the main reason for jumping on the aromatase inhibitor.....fear of a high e2 number or were you truly experiencing symptoms?</p><p></p><p>Keep in mind that you did not have blood work done at true trough as you injected Monday night and did labs Thursday afternoon when you should have waited until Friday morning just before your next injection.</p><p></p><p>As you can see your TT level (12-18 hrs short of your true trough) is high 41.3 nmol/L (1190.2 ng/dL) and your FT is very high (mind you it is the calculated Vermeulen method which is not only outdated but inaccurate).</p><p></p><p>If you had your FT tested using the gold standard Equilibrium Dialysis or Ultrafiltration or just take your TT, SHBG and Albumin and use the newer TruT calculator than you would truly be able to see where your FT level sits.....with a TT 1190.2 ng/dl, Albumin 4.3 g/dL (mean), SHBG 18.4 nmol/L than your <span style="color: rgb(184, 49, 47)">FT (trough) is 45.04 ng/dL</span> (well above the top end of the range).</p><p></p><p>Understand that your peak TT/FT and e2 levels (if your were not taking an a.i.) would be much higher and although I see no major issue running a TT/FT trough level as yours if you felt great overall and your blood markers were in a healthy range.....but the kicker here is your SHBG is somewhat on the lower end so running such a high TT/FT level would have your e2/free e2 very high which could lead to issues for some but seeing as you are using an aromatase inhibitor it brought down your estradiol levels and you stated.....<span style="color: rgb(184, 49, 47)">"So trying to figure out why I'm having on/off ED issues."</span></p><p></p><p>Were you experiencing these issues when you were not using an a.i.?</p><p></p><p>Also keep in mind that your e2 levels may very well be much lower than what your labs show as you had the regular estradiol test done.....not the estradiol sensitive (LC-MS/MS).</p><p></p><p>If you truly were experiencing negative symptoms due to high e2 before the aromatase inhibitor was added to your protocol.....than I would say that since your SHBG is on the lowish end you definitely have room to lower your dose slightly and bring down your TT/FT levels and you could very well drop the a.i. as you may end up not needing it when using a lower overall weekly dose of T and you may very well feel better overall.</p><p></p><p>Have you been donating blood often because your ferritin is lowish?</p><p></p><p>You need to get your ferritin levels higher and definitely start supplementing with iron let alone Vitamin D as your levels can be improved upon.</p></blockquote><p></p>
[QUOTE="madman, post: 170188, member: 13851"] You are Canadian as I can tell you had your blood work done at Lifelabs. How long have you been on said protocol?.....[COLOR=rgb(184, 49, 47)]200mg test E and 1mg adex, split into twice weekly doses. I pin sub Q Mon nights and Fri mornings.[/COLOR] What was the main reason for jumping on the aromatase inhibitor.....fear of a high e2 number or were you truly experiencing symptoms? Keep in mind that you did not have blood work done at true trough as you injected Monday night and did labs Thursday afternoon when you should have waited until Friday morning just before your next injection. As you can see your TT level (12-18 hrs short of your true trough) is high 41.3 nmol/L (1190.2 ng/dL) and your FT is very high (mind you it is the calculated Vermeulen method which is not only outdated but inaccurate). If you had your FT tested using the gold standard Equilibrium Dialysis or Ultrafiltration or just take your TT, SHBG and Albumin and use the newer TruT calculator than you would truly be able to see where your FT level sits.....with a TT 1190.2 ng/dl, Albumin 4.3 g/dL (mean), SHBG 18.4 nmol/L than your [COLOR=rgb(184, 49, 47)]FT (trough) is 45.04 ng/dL[/COLOR] (well above the top end of the range). Understand that your peak TT/FT and e2 levels (if your were not taking an a.i.) would be much higher and although I see no major issue running a TT/FT trough level as yours if you felt great overall and your blood markers were in a healthy range.....but the kicker here is your SHBG is somewhat on the lower end so running such a high TT/FT level would have your e2/free e2 very high which could lead to issues for some but seeing as you are using an aromatase inhibitor it brought down your estradiol levels and you stated.....[COLOR=rgb(184, 49, 47)]"So trying to figure out why I'm having on/off ED issues."[/COLOR] Were you experiencing these issues when you were not using an a.i.? Also keep in mind that your e2 levels may very well be much lower than what your labs show as you had the regular estradiol test done.....not the estradiol sensitive (LC-MS/MS). If you truly were experiencing negative symptoms due to high e2 before the aromatase inhibitor was added to your protocol.....than I would say that since your SHBG is on the lowish end you definitely have room to lower your dose slightly and bring down your TT/FT levels and you could very well drop the a.i. as you may end up not needing it when using a lower overall weekly dose of T and you may very well feel better overall. Have you been donating blood often because your ferritin is lowish? You need to get your ferritin levels higher and definitely start supplementing with iron let alone Vitamin D as your levels can be improved upon. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Lab results. Diagnosing ED/Libido
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