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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Kidney Function: Cystatin C vs. Creatinine in Determining Risk
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<blockquote data-quote="CoastWatcher" data-source="post: 82514" data-attributes="member: 2624"><p>[ATTACH]4132[/ATTACH]</p><p></p><p>Does adding the measurement of cystatin C to that of serum creatinine to determine estimated glomerular filtration rate improve its accuracy? That's the question asked by researchers who undertook a meta-analysis of 11 general population studies (90,750 participants) and five studies of cohorts with chronic kidney disease (2,960 participants) for whom standardized measurements of serum creatinine and cystatin C were available. </p><p></p><p></p><ul> <li data-xf-list-type="ul">Researchers compared the association of the eGFR as calculated by the measurement of creatinine or cystatin C alone or in combination with creatinine, with the overall rate of death, death from cardiovascular causes, and end-stage renal disease.</li> <li data-xf-list-type="ul">Across all eGFR categories, the reclassification of the eGFR to a higher value with the measurement of cystatin C, as opposed to creatinine, was associated with a reduced risk of all three study outcomes; reclassification to a lower eGFR was associated with an increased risk.</li> </ul><p></p><p>The use of cystatin C - alone or in combination with creatinine - strengthens the association between eGFR and the risks of death and end-stage renal disease across diverse populations.</p><p></p><p></p><p><em>The New England Journal of Medicine, 5 September 2013</em></p><p><em></em></p><p><em></em><a href="http://www.nejm.org/doi/full/10.1056/NEJMoa1214234" target="_blank">http://www.nejm.org/doi/full/10.1056/NEJMoa1214234</a></p></blockquote><p></p>
[QUOTE="CoastWatcher, post: 82514, member: 2624"] [ATTACH=CONFIG]4132[/ATTACH] Does adding the measurement of cystatin C to that of serum creatinine to determine estimated glomerular filtration rate improve its accuracy? That's the question asked by researchers who undertook a meta-analysis of 11 general population studies (90,750 participants) and five studies of cohorts with chronic kidney disease (2,960 participants) for whom standardized measurements of serum creatinine and cystatin C were available. [LIST] [*]Researchers compared the association of the eGFR as calculated by the measurement of creatinine or cystatin C alone or in combination with creatinine, with the overall rate of death, death from cardiovascular causes, and end-stage renal disease. [*]Across all eGFR categories, the reclassification of the eGFR to a higher value with the measurement of cystatin C, as opposed to creatinine, was associated with a reduced risk of all three study outcomes; reclassification to a lower eGFR was associated with an increased risk. [/LIST] The use of cystatin C - alone or in combination with creatinine - strengthens the association between eGFR and the risks of death and end-stage renal disease across diverse populations. [I]The New England Journal of Medicine, 5 September 2013 [/I][URL]http://www.nejm.org/doi/full/10.1056/NEJMoa1214234[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Kidney Function: Cystatin C vs. Creatinine in Determining Risk
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