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Mental Health
Jo Cameron, 71, has a rare gene mutation that scientists believe inhibits her from feeling pain or anxiety.
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<blockquote data-quote="Vince" data-source="post: 143561" data-attributes="member: 843"><p>The patient had been diagnosed with osteoarthritis of the hip, which she reported as painless, which was not consistent with the severe degree of <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/joint-degeneration" target="_blank">joint degeneration</a>. At 65 yr of age, she had undergone a hip replacement and was administered only paracetamol 2 g orally on Postoperative days 1 and 2, reporting that she was encouraged to take the paracetamol, but that she did not ask for any analgesics. She was also administered a <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/single-drug-dose" target="_blank">single dose</a> of <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/ms-contin" target="_blank">morphine sulphate</a> 10 mg orally on the first postoperative evening that caused severe <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/nausea-and-vomiting" target="_blank">nausea and vomiting</a> for 2 days. After operation, her pain intensity scores were 0/10 throughout except for one score of 1/10 on the first postoperative evening. Her past surgical history was notable for multiple varicose vein and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/dental-procedure" target="_blank">dental procedures</a> for which she has never required <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/analgesia" target="_blank">analgesia</a>. She also reported a long history of painless injuries (e.g. <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/suturing" target="_blank">suturing</a> of a <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/laceration" target="_blank">laceration</a> and left wrist fracture) for which she did not use analgesics. She reported numerous burns and cuts without pain (<a href="https://www.sciencedirect.com/science/article/pii/S0007091219301382#appsec1" target="_blank">Supplementary Fig. S1</a>), often smelling her burning flesh before noticing any injury, and that these wounds healed quickly with little or no residual scar. She reported eating Scotch bonnet chilli peppers without any discomfort, but a short-lasting ‘pleasant glow’ in her mouth. She described sweating normally in warm conditions.</p><p></p><p><a href="https://www.sciencedirect.com/science/article/pii/S0007091219301382" target="_blank">https://www.sciencedirect.com/science/article/pii/S0007091219301382</a></p><p></p><p>She’d been told that childbirth was going to be painful. But as the hours wore on, nothing bothered her — even without an epidural.</p><p></p><p>“I could feel that my body was changing, but it didn’t hurt me,” recalled the woman, Jo Cameron, who is now 71. She likened it to “a tickle.” Later, she would tell prospective mothers, “Don’t worry, it’s not as bad as people say it is.”</p><p>It was only recently — more than four decades later — that she learned her friends were not exaggerating.</p><p></p><p><a href="https://www.msn.com/en-us/health/health-news/at-71-shes-never-felt-pain-or-anxiety-now-scientists-know-why/ar-BBVlpnB?ocid=spartandhp" target="_blank">At 71, She’s Never Felt Pain or Anxiety. Now Scientists Know Why.</a></p></blockquote><p></p>
[QUOTE="Vince, post: 143561, member: 843"] The patient had been diagnosed with osteoarthritis of the hip, which she reported as painless, which was not consistent with the severe degree of [URL='https://www.sciencedirect.com/topics/medicine-and-dentistry/joint-degeneration']joint degeneration[/URL]. At 65 yr of age, she had undergone a hip replacement and was administered only paracetamol 2 g orally on Postoperative days 1 and 2, reporting that she was encouraged to take the paracetamol, but that she did not ask for any analgesics. She was also administered a [URL='https://www.sciencedirect.com/topics/medicine-and-dentistry/single-drug-dose']single dose[/URL] of [URL='https://www.sciencedirect.com/topics/medicine-and-dentistry/ms-contin']morphine sulphate[/URL] 10 mg orally on the first postoperative evening that caused severe [URL='https://www.sciencedirect.com/topics/medicine-and-dentistry/nausea-and-vomiting']nausea and vomiting[/URL] for 2 days. After operation, her pain intensity scores were 0/10 throughout except for one score of 1/10 on the first postoperative evening. Her past surgical history was notable for multiple varicose vein and [URL='https://www.sciencedirect.com/topics/medicine-and-dentistry/dental-procedure']dental procedures[/URL] for which she has never required [URL='https://www.sciencedirect.com/topics/medicine-and-dentistry/analgesia']analgesia[/URL]. She also reported a long history of painless injuries (e.g. [URL='https://www.sciencedirect.com/topics/medicine-and-dentistry/suturing']suturing[/URL] of a [URL='https://www.sciencedirect.com/topics/medicine-and-dentistry/laceration']laceration[/URL] and left wrist fracture) for which she did not use analgesics. She reported numerous burns and cuts without pain ([URL='https://www.sciencedirect.com/science/article/pii/S0007091219301382#appsec1']Supplementary Fig. S1[/URL]), often smelling her burning flesh before noticing any injury, and that these wounds healed quickly with little or no residual scar. She reported eating Scotch bonnet chilli peppers without any discomfort, but a short-lasting ‘pleasant glow’ in her mouth. She described sweating normally in warm conditions. [URL]https://www.sciencedirect.com/science/article/pii/S0007091219301382[/URL] She’d been told that childbirth was going to be painful. But as the hours wore on, nothing bothered her — even without an epidural. “I could feel that my body was changing, but it didn’t hurt me,” recalled the woman, Jo Cameron, who is now 71. She likened it to “a tickle.” Later, she would tell prospective mothers, “Don’t worry, it’s not as bad as people say it is.” It was only recently — more than four decades later — that she learned her friends were not exaggerating. [URL='https://www.msn.com/en-us/health/health-news/at-71-shes-never-felt-pain-or-anxiety-now-scientists-know-why/ar-BBVlpnB?ocid=spartandhp']At 71, She’s Never Felt Pain or Anxiety. Now Scientists Know Why.[/URL] [/QUOTE]
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Mental Health
Jo Cameron, 71, has a rare gene mutation that scientists believe inhibits her from feeling pain or anxiety.
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