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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
I've been on TRT With Defy Over a Year - Still Can't Figure Out Appropriate Dosage
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<blockquote data-quote="madman" data-source="post: 106003" data-attributes="member: 13851"><p>Of course improvement/relief of low t symptoms is what really matters and numbers on labs should be used as guidance in determining whether one may benefit from decreasing/increasing testosterone/hcg/aromatase inhibitor dose.</p><p></p><p>You definitely can try lowering dose as your total t/free t levels are high if it was taken at trough as you may very well lower e2 by getting your trough into the 900s and and bringing down your free t a little.</p><p></p><p>120 mg/week (60mg every 3.5 days) would be worth trying and then gauge how you feel along the way and have lab work done 6 weeks later.</p><p></p><p>I would discuss with Dr. Saya before changing your protocol.</p><p></p><p>Sure even though you are not experiencing any high e2 symptoms and you feel well overall you may very well still benefit at a lower t dose.</p><p></p><p>I would definitely avoid adding an a.i. if not needed.</p><p></p><p>Sure labs are just numbers to some but they let you know how a specific dose effects your hormones among many other health markers.</p><p></p><p>There are the low and high end of ranges and regarding total t/free t many will argue about what the ranges should be but highly doubtful anyone need to have their total t TROUGH at 1000+ along with free t on the upper end.</p><p></p><p>Regarding free t many will state 2-3% is the norm when in fact searching the literature free testosterone is 2% on average and 98% of testosterone is bound (shbg bound fraction/albumin bound fraction).</p><p></p><p>Many seem to feel they need to have really high total t/free t levels when in fact a lot of men do well having testosterone levels fall in the mid-normal physiological range where as others need to have levels in the high end of the physiological range to experience relief/improvements of their low t symptoms and I doubt anyone needs to be running supra-physiological testosterone levels to benefit from trt.</p><p></p><p>To each his own but I personally feel it is best to use the least amount of testosterone ones physiology needs to experience benefits from trt.</p></blockquote><p></p>
[QUOTE="madman, post: 106003, member: 13851"] Of course improvement/relief of low t symptoms is what really matters and numbers on labs should be used as guidance in determining whether one may benefit from decreasing/increasing testosterone/hcg/aromatase inhibitor dose. You definitely can try lowering dose as your total t/free t levels are high if it was taken at trough as you may very well lower e2 by getting your trough into the 900s and and bringing down your free t a little. 120 mg/week (60mg every 3.5 days) would be worth trying and then gauge how you feel along the way and have lab work done 6 weeks later. I would discuss with Dr. Saya before changing your protocol. Sure even though you are not experiencing any high e2 symptoms and you feel well overall you may very well still benefit at a lower t dose. I would definitely avoid adding an a.i. if not needed. Sure labs are just numbers to some but they let you know how a specific dose effects your hormones among many other health markers. There are the low and high end of ranges and regarding total t/free t many will argue about what the ranges should be but highly doubtful anyone need to have their total t TROUGH at 1000+ along with free t on the upper end. Regarding free t many will state 2-3% is the norm when in fact searching the literature free testosterone is 2% on average and 98% of testosterone is bound (shbg bound fraction/albumin bound fraction). Many seem to feel they need to have really high total t/free t levels when in fact a lot of men do well having testosterone levels fall in the mid-normal physiological range where as others need to have levels in the high end of the physiological range to experience relief/improvements of their low t symptoms and I doubt anyone needs to be running supra-physiological testosterone levels to benefit from trt. To each his own but I personally feel it is best to use the least amount of testosterone ones physiology needs to experience benefits from trt. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
I've been on TRT With Defy Over a Year - Still Can't Figure Out Appropriate Dosage
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