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Mental Health
Is Your Sleep Quality Making You Sick?
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<blockquote data-quote="Nelson Vergel" data-source="post: 68268" data-attributes="member: 3"><p>Humans Out-of-Sync</p><p></p><p>Humans are not immune to the type of clock disruptions documented in mice.</p><p></p><p>Decades of epidemiologic studies show workers with overnight shifts or other schedules out of sync with the light-dark cycle have an increased risk of weight gain and diabetes. Genetic mutations in human clock genes have been associated with obesity and metabolic disease. Conversely, a variation in the gene encoding the melatonin receptor has been linked to a higher risk of developing type-2 diabetes.</p><p></p><p>Even those without genetic mutations or unusual schedules may be at risk of clock disturbances. Thanks to light pollution and growing nighttime use of light bulbs and electronic devices that emit the same wavelengths of light as the sun, many otherwise healthy individuals may experience sleep disturbances or circadian disruptions.</p><p></p><p>“We live in a society where sleep is not respected,” Van Cauter said.</p><p></p><p>But sleep, circadian rhythms, and metabolism make up an “inseparable triad,” she noted. Insufficient sleep has been shown to have a harmful impact on glucose tolerance in many populations including healthy adults, children, hospitalized patients, and those with diabetes, she noted. It's also been shown to reduce resting metabolic rate to a large enough degree that it could translate to a 12.5-pound weight gain in a single year. Sleep restriction also increases hunger, Van Cauter noted. But restoring normal sleep can help reverse these ill effects.</p><p></p><p>“The work so far suggests that being sleep deprived and losing weight are contradictory,” she said. “To optimize weight loss, you need to sleep.”</p><p></p><p></p><p><strong><a href="http://jamanetwork.com/journals/jama/fullarticle/2612679?utm_medium=alert&utm_source=JAMALatestIssue&utm_campaign=04-04-2017" target="_blank">Resetting the Circadian Clock Might Boost Metabolic Health</a></strong></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 68268, member: 3"] Humans Out-of-Sync Humans are not immune to the type of clock disruptions documented in mice. Decades of epidemiologic studies show workers with overnight shifts or other schedules out of sync with the light-dark cycle have an increased risk of weight gain and diabetes. Genetic mutations in human clock genes have been associated with obesity and metabolic disease. Conversely, a variation in the gene encoding the melatonin receptor has been linked to a higher risk of developing type-2 diabetes. Even those without genetic mutations or unusual schedules may be at risk of clock disturbances. Thanks to light pollution and growing nighttime use of light bulbs and electronic devices that emit the same wavelengths of light as the sun, many otherwise healthy individuals may experience sleep disturbances or circadian disruptions. “We live in a society where sleep is not respected,” Van Cauter said. But sleep, circadian rhythms, and metabolism make up an “inseparable triad,” she noted. Insufficient sleep has been shown to have a harmful impact on glucose tolerance in many populations including healthy adults, children, hospitalized patients, and those with diabetes, she noted. It's also been shown to reduce resting metabolic rate to a large enough degree that it could translate to a 12.5-pound weight gain in a single year. Sleep restriction also increases hunger, Van Cauter noted. But restoring normal sleep can help reverse these ill effects. “The work so far suggests that being sleep deprived and losing weight are contradictory,” she said. “To optimize weight loss, you need to sleep.” [b][URL="http://jamanetwork.com/journals/jama/fullarticle/2612679?utm_medium=alert&utm_source=JAMALatestIssue&utm_campaign=04-04-2017"]Resetting the Circadian Clock Might Boost Metabolic Health[/URL][/b] [/QUOTE]
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Mental Health
Is Your Sleep Quality Making You Sick?
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