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Metformin to Augment Strength Training Effective Response in Seniors (MASTERS): study protocol for a randomized controlled trial


https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-017-1932-5


Study has potential potential to make Metformin the new crack for 60+. Personally, I'm finding it is making me weaker in the gym and sleepy afterwards. Some research suggests it might suppress mitochondrial ATP production in muscles by as much as half which would explain. Met does suppress cravings for me. It becomes a pro/con trade off. I like Guided_by_Voices approach of lowering dose and cycling to avoid taking it before heavy workout days. Interested in how that is going or what others are doing.


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