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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Is Long Term HCG Use Toxic to Testicular Cells?
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<blockquote data-quote="Nelson Vergel" data-source="post: 124292" data-attributes="member: 3"><p>Study done in vitro (in the lab) using cells, not mice or humans. </p><p></p><p>I have used HCG for 6 years nonstop and it still works to keep my testicles full. I am only reminded on how well it works when I forget to inject HCG.</p><p></p><p><strong>LONG TERM HCG- Does it stop working due to testicle Leydig cell desensitization? </strong></p><p><strong></strong></p><p>This study of two people did not show issues after 23 months of high doses: <a href="http://www.eje-online.org/content/53/2/315.short" target="_blank">A STUDY OF HUMAN TESTICULAR FUNCTION BY THE USE OF HUMAN MENOPAUSAL GONADOTROPHIN AND OF HUMAN CHORIONIC GONADOTROPHIN IN MALE HYPOGONADOTROPHIC EUNUCHOIDISM AND INFANTILISM : Acta Endocrinologica</a></p><p></p><p>This study showed no long term reduction in efficacy: </p><p><a href="http://www.eje.org/content/77/4/753.short" target="_blank">THE EFFECT OF SHORT AND LONG TERM HUMAN CHORIONIC GONADOTROPHIN (HCG) ADMINISTRATION ON PLASMA TESTOSTERONE LEVELS IN KLINEFELTER'S SYNDROME : Acta Endocrinologica</a></p><p></p><p>This old study in rats probably fueled the misconception, but at these doses in rat cells HCG receptor occupancy returned to normal after 120 hours. How can we extrapolate to humans?<a href="http://www.sciencedirect.com/science/article/pii/0303720777900727" target="_blank">http://www.sciencedirect.com/science...03720777900727</a></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 124292, member: 3"] Study done in vitro (in the lab) using cells, not mice or humans. I have used HCG for 6 years nonstop and it still works to keep my testicles full. I am only reminded on how well it works when I forget to inject HCG. [B]LONG TERM HCG- Does it stop working due to testicle Leydig cell desensitization? [/B] This study of two people did not show issues after 23 months of high doses: [URL="http://www.eje-online.org/content/53/2/315.short"]A STUDY OF HUMAN TESTICULAR FUNCTION BY THE USE OF HUMAN MENOPAUSAL GONADOTROPHIN AND OF HUMAN CHORIONIC GONADOTROPHIN IN MALE HYPOGONADOTROPHIC EUNUCHOIDISM AND INFANTILISM : Acta Endocrinologica[/URL] This study showed no long term reduction in efficacy: [URL="http://www.eje.org/content/77/4/753.short"]THE EFFECT OF SHORT AND LONG TERM HUMAN CHORIONIC GONADOTROPHIN (HCG) ADMINISTRATION ON PLASMA TESTOSTERONE LEVELS IN KLINEFELTER'S SYNDROME : Acta Endocrinologica[/URL] This old study in rats probably fueled the misconception, but at these doses in rat cells HCG receptor occupancy returned to normal after 120 hours. How can we extrapolate to humans?[URL='http://www.sciencedirect.com/science/article/pii/0303720777900727']http://www.sciencedirect.com/science...03720777900727[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Is Long Term HCG Use Toxic to Testicular Cells?
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