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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Is HCG is still needed?
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<blockquote data-quote="madman" data-source="post: 186515" data-attributes="member: 13851"><p>Depends on the individual.....<span style="color: rgb(184, 49, 47)">Is hCG needed?</span></p><p></p><p><span style="color: rgb(0, 0, 0)">To preserve/maintain fertility than yes.</span></p><p><span style="color: rgb(0, 0, 0)"></span></p><p><span style="color: rgb(0, 0, 0)">To prevent/minimize testicular atrophy than yes.</span></p><p><span style="color: rgb(0, 0, 0)"></span></p><p><span style="color: rgb(0, 0, 0)">To enhance mood/libido than it is not a given as some may experience such effects whereas others may feel worse-off.</span></p><p></p><p>To maintain upstream hormones and possibly prevent long-term consequences for health/well-being.....<span style="color: rgb(184, 49, 47)">you be the judge!</span></p><p></p><p></p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/effect-of-trt-vs-hcg-fsh-on-upstream-hormone-pathways.21696/[/URL]</p><p></p><p><em><strong><span style="color: rgb(184, 49, 47)">*Beyond T and DHT, precursor steroids and metabolites are able to elicit androgenic action. </span></strong></em></p><p></p><p><span style="color: rgb(184, 49, 47)"><em><strong>*however, their contribution to androgenic action in the healthy male is as yet unclear. The impact of gonadotropins on the secretion of bioactive androgenic steroids and their precursors is equally unresolved</strong></em><strong>.</strong> </span></p><p><span style="color: rgb(184, 49, 47)"></span></p><p><span style="color: rgb(184, 49, 47)"><em><strong><u>*An optimal endocrine replacement strategy for hypogonadotropic hypogonadal males aims at normalizing all aspects of deficient androgenic action</u>.</strong> </em></span></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p>Take-home point:</p><p></p><p><strong><span style="color: rgb(184, 49, 47)"><em><u>A replacement regimen with combined hCG/rFSH mimics physiologic steroid hormone profiles better than a substitution with exogenous testosterone</u>.</em></span><em> <span style="color: rgb(26, 188, 156)"><u>The documented differences in steroid profiles on testosterone replacement in hypogonadal males with absent or severely reduced endogenous LH and FSH secretion may have long term consequences for health and wellbeing. Specifically, body composition, bone health, glucose, and lipid metabolism, salt and water balance, cognition, mood, sleep, and sexual function could be affected</u>.</span> <span style="color: rgb(184, 49, 47)">The steroidogenic differences could also be relevant for gonadotropin-suppressive treatments with long-acting testosterone preparations in males with primary hypogonadism. To what extent this hypothesis is true, should be addressed in future clinical studies.</span></em></strong></p></blockquote><p></p>
[QUOTE="madman, post: 186515, member: 13851"] Depends on the individual.....[COLOR=rgb(184, 49, 47)]Is hCG needed?[/COLOR] [COLOR=rgb(0, 0, 0)]To preserve/maintain fertility than yes. To prevent/minimize testicular atrophy than yes. To enhance mood/libido than it is not a given as some may experience such effects whereas others may feel worse-off.[/COLOR] To maintain upstream hormones and possibly prevent long-term consequences for health/well-being.....[COLOR=rgb(184, 49, 47)]you be the judge![/COLOR] [URL unfurl="true"]https://www.excelmale.com/forum/threads/effect-of-trt-vs-hcg-fsh-on-upstream-hormone-pathways.21696/[/URL] [I][B][COLOR=rgb(184, 49, 47)]*Beyond T and DHT, precursor steroids and metabolites are able to elicit androgenic action. [/COLOR][/B][/I] [COLOR=rgb(184, 49, 47)][I][B]*however, their contribution to androgenic action in the healthy male is as yet unclear. The impact of gonadotropins on the secretion of bioactive androgenic steroids and their precursors is equally unresolved[/B][/I][B].[/B] [I][B][U]*An optimal endocrine replacement strategy for hypogonadotropic hypogonadal males aims at normalizing all aspects of deficient androgenic action[/U].[/B] [/I][/COLOR] Take-home point: [B][COLOR=rgb(184, 49, 47)][I][U]A replacement regimen with combined hCG/rFSH mimics physiologic steroid hormone profiles better than a substitution with exogenous testosterone[/U].[/I][/COLOR][I] [COLOR=rgb(26, 188, 156)][U]The documented differences in steroid profiles on testosterone replacement in hypogonadal males with absent or severely reduced endogenous LH and FSH secretion may have long term consequences for health and wellbeing. Specifically, body composition, bone health, glucose, and lipid metabolism, salt and water balance, cognition, mood, sleep, and sexual function could be affected[/U].[/COLOR] [COLOR=rgb(184, 49, 47)]The steroidogenic differences could also be relevant for gonadotropin-suppressive treatments with long-acting testosterone preparations in males with primary hypogonadism. To what extent this hypothesis is true, should be addressed in future clinical studies.[/COLOR][/I][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Is HCG is still needed?
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