ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Is GnRH suppression hurting us?
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="Cataceous" data-source="post: 236874" data-attributes="member: 38109"><p>A tip of the hat to [USER=39208]@ajax31[/USER] for an interesting link involving GnRH and cognition. It appears that a lack of GnRH contributes to cognitive deficits in Down Syndrome. </p><p>[URL unfurl="true"]https://futurism.com/neoscope/scientists-treatment-improve-congition-down-syndrome[/URL]</p><p></p><p style="margin-left: 20px"><em>In a pilot experiment involving mice with three copies of chromosome 21, a team led by neuroscientist Vincent Prevot of the University of Lille in France found that increasing the levels of GnRH using microRNAs was able to reverse the effects Down syndrome had on the animals' olfactory senses and other cognitive deficits.</em></p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px"><em>Of course, an animal study doesn't prove anything for humans. But a followup experiment involving seven men with Down syndrome who received GnRH from a pump under their skin showed hopeful results as well.</em></p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px"><em>"Six out of seven patients improved their cognitive tests by 20 to 30 percent," Prevot told Scientific American.</em></p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px"><em>"Even more amazing, we saw that functional connectivity was tremendously increased in all seven in cortical areas involved in speech and 3D orientation," Prevot added, noting that the men experienced improvements in verbal comprehension and temporary memory and attention.</em></p><p></p><p>See also:</p><p>[URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/36048943/[/URL]</p><p></p><p style="margin-left: 20px"><em><strong>GnRH thus plays a crucial role in olfaction and cognition</strong>, and pulsatile GnRH therapy holds promise to improve cognitive deficits in DS.</em></p><p></p><p>Other comments related to the work:</p><p>[URL unfurl="true"]https://www.eurekalert.org/news-releases/963122[/URL]</p><p></p><p style="margin-left: 20px"><em>Recent research has suggested that olfaction loss and male infertility is also a characteristic of GnRH deficiency, and that GnRH may play a role in higher brain functions, such as cognition.</em></p></blockquote><p></p>
[QUOTE="Cataceous, post: 236874, member: 38109"] A tip of the hat to [USER=39208]@ajax31[/USER] for an interesting link involving GnRH and cognition. It appears that a lack of GnRH contributes to cognitive deficits in Down Syndrome. [URL unfurl="true"]https://futurism.com/neoscope/scientists-treatment-improve-congition-down-syndrome[/URL] [INDENT][I]In a pilot experiment involving mice with three copies of chromosome 21, a team led by neuroscientist Vincent Prevot of the University of Lille in France found that increasing the levels of GnRH using microRNAs was able to reverse the effects Down syndrome had on the animals' olfactory senses and other cognitive deficits.[/I][/INDENT] [INDENT][I][/I][/INDENT] [INDENT][I]Of course, an animal study doesn't prove anything for humans. But a followup experiment involving seven men with Down syndrome who received GnRH from a pump under their skin showed hopeful results as well.[/I][/INDENT] [INDENT][I][/I][/INDENT] [INDENT][I]"Six out of seven patients improved their cognitive tests by 20 to 30 percent," Prevot told Scientific American.[/I][/INDENT] [INDENT][/INDENT] [INDENT][I]"Even more amazing, we saw that functional connectivity was tremendously increased in all seven in cortical areas involved in speech and 3D orientation," Prevot added, noting that the men experienced improvements in verbal comprehension and temporary memory and attention.[/I][/INDENT] See also: [URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/36048943/[/URL] [INDENT][I][B]GnRH thus plays a crucial role in olfaction and cognition[/B], and pulsatile GnRH therapy holds promise to improve cognitive deficits in DS.[/I][/INDENT] Other comments related to the work: [URL unfurl="true"]https://www.eurekalert.org/news-releases/963122[/URL] [INDENT][I]Recent research has suggested that olfaction loss and male infertility is also a characteristic of GnRH deficiency, and that GnRH may play a role in higher brain functions, such as cognition.[/I][/INDENT] [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Is GnRH suppression hurting us?
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top